Proteomics

Dataset Information

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Interactors of USP7-TRAF domain in rat neurons


ABSTRACT: USP7 protein has a TRAF domain near the N-terminus, which has been reported to bind to many substrates of USP7 in cancer cells. Here we looked for interactors of this USP7-TRAF domain in primary rat neurons. We expressed and immunprecipitated the FLAG-tagged USP7-TRAF domain in neurons. We also used the binding-deficient mutant TRAF RDW as negative control. The immunoprecipitated USP7-TRAF along with its interactors were profiled with LC-MS/MS.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Rattus Norvegicus (rat)

TISSUE(S): Primary Neuron, Cell Culture

SUBMITTER: Hao Chen  

LAB HEAD: Albert H. Kim

PROVIDER: PXD043225 | Pride | 2025-02-24

REPOSITORIES: pride

Dataset's files

Source:
Action DRS
389748_j40091_HC_SPG_rat.mzIdentML Mzid
389749_j40090_HC_SPG_rat.mzIdentML Mzid
389750_j40089_HC_SPG_rat.mzIdentML Mzid
389751_j40088_HC_SPG_rat.mzIdentML Mzid
389752_j40087_HC_SPG_rat.mzIdentML Mzid
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