Dataset Information

Avian pathogenic Escherichia coli infection causes infiltration of heterophilic granulocytes of chick tracheal by the complement and coagulation cascades pathway

ABSTRACT: Tracheal mucosal epithelial cells were scraped at 12 and 24 hours of infection, frozen in liquid nitrogen and stored at -80°C. The cells were sent to a biotechnology company for TMT quantitative proteomic analysis. The cells were sent to a biotech company for TMT quantitative proteomics analysis.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Gallus Gallus (chicken)

TISSUE(S): Epithelial Cell, Saliva

SUBMITTER: Ziqi Li

LAB HEAD: Ziqi Li

PROVIDER: PXD044411 | Pride | 2024-01-26

REPOSITORIES: Pride

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Avian pathogenic Escherichia coli infection causes infiltration of heterophilic granulocytes of chick tracheal by the complement and coagulation cascades pathway.

Li Ziqi Z Qi Zhao Z Wang Xiaoru X Lu Liting L Wang Haiyang H He Zhenjie Z Chen Zhe Z Shao Ying Y Tu Jian J Song Xiangjun X

BMC veterinary research 20231208 1

<h4>Background</h4>Avian pathogenic Escherichia coli (APEC) causes tracheal damage and heterophilic granulocytic infiltration and inflammation in infected chicks. In this study, we infected chick tracheal tissue with strain AE17 and produced pathological sections with proteomic sequencing. We compared the results of pathological sections from the APEC-infected group with those from the PBS control group; the pathological sections from the experimental group showed hemorrhage, fibrinization, and ...[more]

PMID: 38066606

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