Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress)
TISSUE(S): Plant Cell, Seedling
SUBMITTER: Mathias Tankmar
LAB HEAD: Peter Brodersen
PROVIDER: PXD045801 | Pride | 2023-11-28
REPOSITORIES: Pride
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EMBO reports 20231127 12
N6-methyladenosine (m<sup>6</sup> A) in mRNA is key to eukaryotic gene regulation. Many m<sup>6</sup> A functions involve RNA-binding proteins that recognize m<sup>6</sup> A via a YT521-B Homology (YTH) domain. YTH domain proteins contain long intrinsically disordered regions (IDRs) that may mediate phase separation and interaction with protein partners, but whose precise biochemical functions remain largely unknown. The Arabidopsis thaliana YTH domain proteins ECT2, ECT3, and ECT4 accelerate or ...[more]