Ontology highlight
ABSTRACT:
INSTRUMENT(S): timsTOF Pro
ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast) Saccharomyces Cerevisiae
SUBMITTER: Natalia Kunowska
LAB HEAD: Ulrich Stelzl
PROVIDER: PXD046068 | Pride | 2024-05-22
REPOSITORIES: pride
Action | DRS | |||
---|---|---|---|---|
Samples_description.txt | Txt | |||
VM230717-lib.predicted.speclib | Other | |||
VM230717-lib.tsv | Tabular | |||
VM230717.gg_matrix.tsv | Tabular | |||
VM230717.pg_matrix.tsv | Tabular |
Items per page: 1 - 5 of 38 |
Nucleic acids research 20240201 4
During ribosome biogenesis a plethora of assembly factors and essential enzymes drive the unidirectional maturation of nascent pre-ribosomal subunits. The DEAD-box RNA helicase Dbp10 is suggested to restructure pre-ribosomal rRNA of the evolving peptidyl-transferase center (PTC) on nucleolar ribosomal 60S assembly intermediates. Here, we show that point mutations within conserved catalytic helicase-core motifs of Dbp10 yield a dominant-lethal growth phenotype. Such dbp10 mutants, which stably as ...[more]