Ontology highlight
ABSTRACT:
INSTRUMENT(S): Synapt MS
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Blood Serum
DISEASE(S): Prostate Adenocarcinoma
SUBMITTER: Lee Gethings
LAB HEAD: Lee Gethings
PROVIDER: PXD046530 | Pride | 2024-01-26
REPOSITORIES: Pride
Items per page: 5 1 - 5 of 8 |
Spick Matt M Muazzam Ammara A Pandha Hardev H Michael Agnieszka A Gethings Lee A LA Hughes Christopher J CJ Munjoma Nyasha N Plumb Robert S RS Wilson Ian D ID Whetton Anthony D AD Townsend Paul A PA Geifman Nophar N
Heliyon 20231119 12
There is an unmet need for improved diagnostic testing and risk prediction for cases of prostate cancer (PCa) to improve care and reduce overtreatment of indolent disease. Here we have analysed the serum proteome and lipidome of 262 study participants by liquid chromatography-mass spectrometry, including participants diagnosed with PCa, benign prostatic hyperplasia (BPH), or otherwise healthy volunteers, with the aim of improving biomarker specificity. Although a two-class machine learning model ...[more]