The role of HnrnpF/H as a driver of Oligoteratozoospermia
Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 6600
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Semen, Sperm
DISEASE(S): Male Infertility
SUBMITTER: 
Christoph Krisp
LAB HEAD: Mark Baker
PROVIDER: PXD046594 | Pride | 2024-08-09
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| Fertile_1-1_SWATH.wiff | Wiff | |||
| Fertile_1-1_SWATH.wiff.scan | Wiff | |||
| Fertile_1-2_SWATH.wiff | Wiff | |||
| Fertile_1-2_SWATH.wiff.scan | Wiff | |||
| Fertile_1.wiff | Wiff |
Items per page: 5 1 - 5 of 57 |
Publications
The role of HnrnpF/H as a driver of oligoteratozoospermia.
Netherton Jacob K JK Ogle Rachel A RA Robinson Benjamin R BR Molloy Mark M Krisp Christoph C Velkov Tony T Casagranda Franca F Dominado Nicole N Silva Balbin Villaverde Ana Izabel AI Zhang Xu Dong XD Hime Gary R GR Baker Mark A MA
iScience 20240606 7
Male subfertility or infertility is a common condition often characterized by men producing a low number of sperm with poor quality. To gain insight into this condition, we performed a quantitative proteomic analysis of semen samples obtained from infertile and fertile men. At least 6 proteins showed significant differences in regulation of alternatively spliced isoforms. To investigate this link between aberrant alternative splicing and production of poor-quality spermatozoa, we overexpressed t ...[more]
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