Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Brain
SUBMITTER: Manveen Sethi
LAB HEAD: Joseph Zaia
PROVIDER: PXD047129 | Pride | 2024-05-10
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
P2_M2_08092019RE.RAW | Raw | |||
P2_M2_08092019RE.mgf | Mgf | |||
P2_M2_08092019RE.mzML | Mzml | |||
P2_M2_08092019_01.mgf | Mgf | |||
P2_M2_08092019_01.mzML | Mzml |
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Cell reports 20240426 5
Recent findings show that effective integration of novel information in the brain requires coordinated processes of homo- and heterosynaptic plasticity. In this work, we hypothesize that activity-dependent remodeling of the peri-synaptic extracellular matrix (ECM) contributes to these processes. We show that clusters of the peri-synaptic ECM, recognized by CS56 antibody, emerge in response to sensory stimuli, showing temporal and spatial coincidence with dendritic spine plasticity. Using CS56 co ...[more]