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Identification of immunoreactive proteins in murine sera after immunization with outer membrane vesicles isolated from Francisella tularensis subsp. holarctica strain FSC200

ABSTRACT: Secretion of outer membrane vesicles (OMV) presents an important phenomenon in Gram-negative bacteria and they play multiple roles in their lifestyle including virulence and host-pathogen interaction. Francisella tularensis secretes unusually shaped tubular OMV filled with immunoreactive material and virulence factors. Mice were immunized with OMV isolated from Francisella tularensis subsp. holarctica, fully virulent strain FSC200. Their sera were then used for detection of immunoreactive proteins.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Francisella Tularensis Subsp. Holarctica Fsc200

DISEASE(S): Tularemia

SUBMITTER: Jana Klimentova

LAB HEAD: Jiri Stulik

PROVIDER: PXD047830 | Pride | 2024-02-22

REPOSITORIES: Pride

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			Action	DRS
	08172020_134_JK_12-2020-OMV_1.msf	Msf
	08172020_134_JK_12-2020-OMV_1.raw	Raw
	08172020_136_JK_12-2020-OMV_2.msf	Msf
	08172020_136_JK_12-2020-OMV_2.raw	Raw
	08172020_138_JK_12-2020-OMV_3.msf	Msf

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Proteomic characterization and label-free comparison of outer membrane vesicles from Francisella tularensis subsp. holarctica strain FSC200 isolated from different cultivation conditions

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