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Immunoseroproteomic profiling in prostate cancer

ABSTRACT: Mass spectrometry analysis of immunoreactive protein spots revealed that seveal prostate cancer patient sera had autoantibodies to a number of proteins associated with both the glycolysis and plasminogen pathways.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell

DISEASE(S): Prostate Adenocarcinoma

SUBMITTER: Tino Sanchez

LAB HEAD: Carlos Casiano

PROVIDER: PXD003968 | Pride | 2017-01-06

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	A101(01).pride.mgf.gz	Mgf
	A101(01).pride.mztab.gz	Mztab
	A10101.mgf	Mgf
	A10101.msf	Msf
	A10101.mzid.gz	Mzid

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1 - 5 of 414

Publications

Immunoseroproteomic Profiling in African American Men with Prostate Cancer: Evidence for an Autoantibody Response to Glycolysis and Plasminogen-Associated Proteins.

Sanchez Tino W TW Zhang Guangyu G Li Jitian J Dai Liping L Mirshahidi Saied S Wall Nathan R NR Yates Clayton C Wilson Colwick C Montgomery Susanne S Zhang Jian-Ying JY Casiano Carlos A CA

Molecular & cellular proteomics : MCP 20161014 12

African American (AA) men suffer from a disproportionately high incidence and mortality of prostate cancer (PCa) compared with other racial/ethnic groups. Despite these disparities, African American men are underrepresented in clinical trials and in studies on PCa biology and biomarker discovery. We used immunoseroproteomics to profile antitumor autoantibody responses in AA and European American (EA) men with PCa, and explored differences in these responses. This minimally invasive approach dete ...[more]

PMID: 27742740

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Identification of immunoreactive proteins of Mycobacterium avium subsp. Paratuberculosis

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