Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture, Early Embryonic Cell
SUBMITTER: Eric Ottesen
LAB HEAD: Ravindra Singh
PROVIDER: PXD048160 | Pride | 2024-05-23
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
P1145-01_Ctrl_1.msf | Msf | |||
P1145-01_Ctrl_1.raw | Raw | |||
P1145-02_1ug_Ctrl_2.msf | Msf | |||
P1145-02_1ug_Ctrl_2.raw | Raw | |||
P1145-03_Ctrl_3.msf | Msf |
Items per page: 1 - 5 of 19 |
Scientific reports 20240507 1
Spinal muscular atrophy (SMA) genes, SMN1 and SMN2 (hereinafter referred to as SMN1/2), produce multiple circular RNAs (circRNAs), including C2A-2B-3-4 that encompasses early exons 2A, 2B, 3 and 4. C2A-2B-3-4 is a universally and abundantly expressed circRNA of SMN1/2. Here we report the transcriptome- and proteome-wide effects of overexpression of C2A-2B-3-4 in inducible HEK293 cells. Our RNA-Seq analysis revealed altered expression of ~ 15% genes (4172 genes) by C2A-2B-3-4. About half of the a ...[more]