Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Brain
SUBMITTER: Antrix Jain
LAB HEAD: Benjamin Deneen
PROVIDER: PXD048170 | Pride | 2024-09-09
REPOSITORIES: Pride
Items per page: 1 - 5 of 70 |
Nature 20240731 8026
Bidirectional communication between tumours and neurons has emerged as a key facet of the tumour microenvironment that drives malignancy<sup>1,2</sup>. Another hallmark feature of cancer is epigenomic dysregulation, in which alterations in gene expression influence cell states and interactions with the tumour microenvironment<sup>3</sup>. Ependymoma (EPN) is a paediatric brain tumour that relies on epigenomic remodelling to engender malignancy<sup>4,5</sup>; however, how these epigenetic mechani ...[more]