Proteomics

Dataset Information

0

Autophagosome content profiling in TBK1-E696K knockin MEFs


ABSTRACT: To determine how the mutant TBK1-E696K protein impacts autophagosomes, we performed autophagosome content profiling using protease protection coupled APEX2 proximity proteomics of autophagosomes of homozygous TBK1-E696K knockin and wiltype mouse embryonic fibroblasts (MEFs) transfected with a APEX2-LC3 as previously described in Zellner et al. 2021 Molecular Cell.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Embryo, Fibroblast

DISEASE(S): Huntington Disease

SUBMITTER: Christian Behrends  

LAB HEAD: Christian Behrends

PROVIDER: PXD048795 | Pride | 2024-03-16

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
20200506_SZ937.raw Raw
20200506_SZ938.raw Raw
20200506_SZ939.raw Raw
20200506_SZ940.raw Raw
20200506_SZ941.raw Raw
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