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Cryphonectria parasitic Smt3 deletion

ABSTRACT: To explore the molecular mechanism of SUMOylation in phenotype, we performed a label-free proteomic analysis of wildtype vs ΔCpSmt3 mycelia. The strains were cultured on PDA for 10 days.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Cryphonectria Parasitica Ep155

SUBMITTER: Shuangcai Li

LAB HEAD: Baoshan Chen

PROVIDER: PXD051781 | Pride | 2024-06-23

REPOSITORIES: Pride

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Publications

<i>CpSmt3</i>, an ortholog of small ubiquitin-like modifier, is essential for growth, organelle function, virulence, and antiviral defense in <i>Cryphonectria parasitica</i>.

Li Shuangcai S Chen Fengyue F Wei Xiangyu X Yuan Luying L Qin Jiayao J Li Ru R Chen Baoshan B

Frontiers in microbiology 20240509

<h4>Introduction</h4>SUMOylation is an important post-translational modification that regulates the expression, localization, and activity of substrate proteins, thereby participating in various important cellular processes such as the cell cycle, cell metabolism, gene transcription, and antiviral activity. However, the function of SUMOylation in phytopathogenic fungi has not yet been adequately explored.<h4>Methods</h4>A comprehensive analysis composed of proteomics, affinity pull-down, molecul ...[more]

PMID: 38784801

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