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Zika virus remodels the IGF2BP2 and VCP cellular interactome

ABSTRACT: Zika virus (ZIKV) infection causes significant human disease that, with no approved treatment or vaccine, constitutes a major public health concern. Its life cycle entirely relies on the cytoplasmic fate of the viral RNA genome (vRNA) through a fine-tuned equilibrium between vRNA translation, replication and packaging into new virions, all within virus-induced replication organelles (vRO). In this study, we characterized the cellular interactome of insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and the valosin-containing protein (VCP, also known as p97)

INSTRUMENT(S): timsTOF Pro

ORGANISM(S): Homo Sapiens (human) Dengue Virus 2 Zika Virus

TISSUE(S): Liver

DISEASE(S): Zika Virus Congenital Syndrome,Dengue Disease

SUBMITTER: Pietro Scaturro

LAB HEAD: Pietro Scaturro

PROVIDER: PXD052835 | Pride | 2024-10-28

REPOSITORIES: Pride

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			Action	DRS
	221015_PS_CB_IP_IMP2_DENV_1_Slot1-48_1_3209.d.zip	Other
	221015_PS_CB_IP_IMP2_DENV_2_Slot1-49_1_3210.d.zip	Other
	221015_PS_CB_IP_IMP2_DENV_3_Slot1-50_1_3211.d.zip	Other
	221015_PS_CB_IP_IMP2_DENV_4_Slot1-51_1_3212.d.zip	Other
	221015_PS_CB_IP_IMP2_DENV_5_Slot1-52_1_3213.d.zip	Other

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