Proteomics

Dataset Information

0

Alterations in the nascent proteome during translation attenuation in response to mitochondrial stress induced by carbonyl cyanide m-chlorophenyl hydrazine (CCCP) and in response to EEF1A1 knockdown


ABSTRACT: This submission is a part of a proteomic resource consisting of four independent datasets and their meta-analysis which describe: the detailed landscape of changes in the nascent proteome at high temporal resolution with 30 min intervals upon rapid and reversible global translation attenuation in response to transient mitochondrial membrane depolarization and during the subsequent recovery of physiological translation upon the relief of this stress (PXD043942), comparison of nascent proteome alterations in response to two types of challenge to protein homeostasis – proteasome inhibition and mitochondrial inner membrane depolarization (this submission, datasets expII and expIV) and finally nascent proteome alterations happening after silencing of elongation factor EEF1A1 in untreated and stress conditions (this submission, dataset expIII).

INSTRUMENT(S): Q Exactive HF-X

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Hek-293t Cell

SUBMITTER: Remigiusz Serwa  

LAB HEAD: Agnieszka Chacinska

PROVIDER: PXD054502 | Pride | 2024-10-02

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
TMS137_C18_fr1_2.raw Raw
TMS137_C18_fr3_4.raw Raw
TMS137_C18_fr5_6.raw Raw
TMS137_C18_fr7_8.raw Raw
TMS137_SCX_fr1_3.raw Raw
Items per page:
1 - 5 of 28

Similar Datasets

2024-10-02 | PXD043942 | Pride
2014-01-18 | E-GEOD-54207 | biostudies-arrayexpress
2022-11-11 | PXD021063 | Pride
2016-10-06 | PXD004915 | Pride
2024-05-24 | PXD042577 | Pride
2016-10-06 | PXD004929 | Pride
2021-07-02 | PXD025169 | Pride
2023-10-24 | PXD042395 | Pride
2023-09-29 | PXD041645 | Pride
2023-05-24 | PXD035992 | Pride