Dataset Information

To identify the phenol soluble modulins whose production are primarily affected by SarZ in Staphylococcus epidermidis

ABSTRACT: Phenol-soluble modulins (PSMs) are a class of short, amphipathic, α-helical peptides, which have strong cytolytic effects toward leukocytes and erythrocytes in S. epidermidis. SarZ is a key transcriptional regulator required for the expression of virulence factors. To determine whether the production of PSMs is under the control of SarZ, a sarZ deletion mutant strain was generated. Through butanol extraction of the spent medium and subsequent HPLC-MS/MS analysis, the amounts of PSMs were compared between the sarZ mutant and its parent strain.

INSTRUMENT(S): Orbitrap Exploris 240

ORGANISM(S): Staphylococcus Epidermidis Rp62a

SUBMITTER: Tao Zhu

LAB HEAD: Tao Zhu

PROVIDER: PXD057952 | Pride | 2024-12-05

REPOSITORIES: Pride

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Publications

The US Bureau of the Census in the nineteenth century.

Anderson M M

Social history of medicine : the journal of the Society for the Social History of Medicine 19911201 3

PMID: 11612630

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