Project description:Erysipelothrix rhusiopathiae is generally regarded as an opportunistic pathogen that causes erysipelas in swine and other diseases in several mammalian and avian species.This study aimed to perform a whole-genomic analysis of the transcriptional responses of a pig heart to virulent and avirulent strains and PBS by using Affymetrix Porcine Gene 1.0 ST Microarray to elucidate the immune responses of hosts to E. rhusiopathiae.
Project description:Data on the draft genome sequence of Erysipelothrix rhusiopathiae strain VR-2 is presented in this report. E. rhusiopathiae strain VR-2 is a commercial attenuated vaccine widely used in Russia and a number European countries for immunization of pigs against swine erysipelas. The draft genome sequence of 1,704,727 bp in length included 1415 protein sequences, 50 tRNA genes and 3 rRNA genes according NCBI Prokaryotic Genomes Automatic Annotation Pipeline results. The draft genome sequence data of E. rhusiopathiae strain VR-2 is available in GenBank under the accession nos. RJTK00000000.1, PRJNA504614 and SAMN10395786 for Genome, Bioproject and Biosample, respectively. The obtained sequence data may be helpful for searching genetic markers of VR-2, aimed to develop assays to discriminate between field isolates and this vaccine strain of E. rhusiopathiae.