Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Xenopus laevis

ABSTRACT: The complex of LARP6 and DNAAF6 controls the expression of alpha-tubulin protein during differentiation of multi-ciliated cells.

PROVIDER: PRJDB14674 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	DRR415135_1.fastq.gz	Fastqsanger.gz
	DRR415135_2.fastq.gz	Fastqsanger.gz
	DRR415136_1.fastq.gz	Fastqsanger.gz
	DRR415136_2.fastq.gz	Fastqsanger.gz
	DRR415137_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 24

Similar Datasets

Xenopus laevis

Project description:microRNAs signatures of Xenopus laevis embryo epidermis at stage 11 (non ciliated) and 26 (ciliated) using high throughput sequencing

| PRJNA129201 | ENA

Cilia proteome isolated from the multi-ciliated cells of Xenopus laevis embryo epidermis

Project description:We characterized the cilia proteome isolated from the multi-ciliated cells of Xenopus laevis embryo epidermis.

2019-11-15 | PXD010722 | Pride

microRNAs signatures of Xenopus laevis embryo epidermis at stage 11 (non ciliated) and 26 (ciliated) using high throughput sequencing

Project description:Epidermis of Xenopus embryos forms a mucociliary epithelium constituted of basal, scattered, secreting and ciliated cells and is histologically similar to human airway mucociliary epithelium. We compared microRNAs signatures of epidermis of Xenopus embryos at stage 11.5 (gastrula, non ciliated epidermis) and at stage 26 (tailbud, ciliated epidermis). 2 technical replicates of a pool of 50 explants for each stage 11.5 (non ciliated) and 26 (ciliated) of Xenopus laevis development

2011-06-06 | E-GEOD-22146 | biostudies-arrayexpress

Xenopus laevis

Project description:The protein kinase MLTK Is a key regulator for chondrogenesis.

| PRJNA148377 | ENA

Xenopus laevis

Project description:Multicilin promotes centriole assembly and ciliogenesis during multiciliate cell differentiation.

| PRJNA147733 | ENA

Geminin-regulated genes in the Xenopus laevis embryonic ectoderm

Project description:Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo: Transient maintenance of a pluripotent embryonic cell population followed by the onset of multi-lineage commitment is a fundamental aspect of development. However, molecular regulation of this transition is not well characterized in vivo. Here we demonstrate that the nuclear protein Geminin is required to restrain commitment and spatially restrict mesoderm, endoderm, and non-neural ectoderm to their proper locations in the Xenopus embryo. We used microarray analyses to demonstrate that Geminin overexpression represses many genes associated with cell commitment and differentiation, while elevating expression levels of genes that maintain pluripotent early and immature neurectodermal cell states. We characterized Geminin’s relationship to cell signaling and found that Geminin broadly represses Activin-, FGF-, and BMP-mediated cell commitment. Conversely, Geminin knockdown enhances commitment responses to growth factor signaling and causes ectopic mesodermal, endodermal, and epidermal fate commitment in the embryo. We also characterized Geminin’s functional relationship with transcription factors that had similar activities and found that Geminin represses commitment independent of Oct4 ortholog (Oct25/60) activities, but depends upon intact Polycomb repressor function. Consistent with this, chromatin immunoprecipitation assays directed at mesodermal genes demonstrate that Geminin promotes Polycomb binding and Polycomb-mediated repressive histone modifications, while inhibiting modifications associated with gene activation. This work defines Geminin as an essential regulator of the embryonic transition from pluripotency through early multi-lineage commitment, and demonstrates that functional cooperativity between Geminin and Polycomb contributes to this process.

2010-12-06 | GSE25158 | GEO

Xenopus laevis

Project description:Thyroid Hormone (TH) Controls The Remodeling Of The Pancreas And The Liver, Part C

| PRJNA123085 | ENA

Xenopus laevis

Project description:Thyroid Hormone (TH) Controls The Remodeling Of The Pancreas And The Liver, Part B

| PRJNA123083 | ENA

Xenopus laevis

Project description:Thyroid Hormone (TH) Controls The Remodeling Of The Pancreas And The Liver, Part A

| PRJNA123097 | ENA

microRNAs signatures of Xenopus laevis embryo epidermis at stage 11 (non ciliated) and 26 (ciliated) using high throughput sequencing

2011-06-07 | GSE22146 | GEO