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Acinetobacter baumannii strain:ATCC BAA-1605

ABSTRACT: Whole genome assembly of Multi-drug resistant Acinetobacter baumannii ATCC BAA-1605

PROVIDER: PRJDB16714 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	DRR505152_1.fastq.gz	Fastqsanger.gz
	DRR505153_1.fastq.gz	Fastqsanger.gz
	DRR505153_2.fastq.gz	Fastqsanger.gz

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Acinetobacter baumannii strain:ATCC #BAA-1605

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Comparison of the gene expression profiles of different strains of A. baumannii by microarrays

Project description:In the present work we compare the gene expression profile of A. baumannii and a mutant knock-out strain of A. baumannii lacking a small RNA gene 13573 and the corresponding small RNA 13573 over-producing strain. The main objective is to recognize the main pathways in which the small RNA 13573 is involved. Moreover, the same wild type strain was used to infect mice and was further analyzed after the infection with the aim of finding genes differentially expressed in vivo. Three biological replicates have been performed for each comparison. The RNA collection from Acinetobacter baumannii strain over-expresing the small RNA (sample 13573) was compared with this isolated from A. baumannii harboring the empty vector (PETRA sample) while gene expression in the knock-out strain (KO sample) was compared with the wild type strain Acinetobacter baumannii ATCC 17978 (ATCC sample). The RNA from A.baumannii recovered from the infected animals (INF sample) was compared with the wild type (ATCC).

2016-08-01 | E-GEOD-60348 | biostudies-arrayexpress

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Project description:Purpose: The goal of this study was to elucidate the collateral effects associated with OXA-23 overexpression on the Acinetobacter baumannii global transcriptome. Results: Besides the 99.73-fold increase in blaOXA-23 transcript upon IPTG induction, no other transcripts showed more than a 2-fold change compared to the wildtype control. This suggests that OXA-23 over expression to levels similarly observed in multi drug resistant A. baumannii clinical isolates does not effect the transcriptome.

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N-acetylation in Acinetobacter baumannii

Project description:Characterization of Nalpha- and Nexpsilon-acetylation in Acinetobacter baumannii ATCC 17978 using different analytical approaches (isoelectrofocusing, strong cation exchange, immunoprecipitation, CNBr enrichment, and high resolutive and accurate mass spectrometry).

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