Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gut metagenome

ABSTRACT: Microbial community analysis of feces of wild western lowland gorillas

PROVIDER: PRJDB7910 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	DRR166230_1.fastq.gz	Fastqsanger.gz
	DRR166230_2.fastq.gz	Fastqsanger.gz
	DRR166231_1.fastq.gz	Fastqsanger.gz
	DRR166231_2.fastq.gz	Fastqsanger.gz
	DRR166232_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 10

Similar Datasets

Western lowland gorilla (Gorilla gorilla gorilla)

Project description:Gut microbiome of zoo-housed Western lowland gorillas

| PRJNA827108 | ENA

gut metagenome

Project description:Western lowland gorrila individual fecal microbial communities from Wisconsin, USA - Go1022B metagenome metagenome

| PRJNA340484 | ENA

gut metagenome

Project description:Western lowland gorrila individual fecal microbial communities from Wisconsin, USA - Go1022A metagenome metagenome

| PRJNA340483 | ENA

Project description:Altered gut microbial metabolism provides insights into cardiometabolic disease in zoo-housed western lowland gorillas

| PRJNA995885 | ENA

pig gut metagenome

Project description:piglet feces microbial community diversity

| PRJNA300609 | ENA

gut metagenome

Project description:Wild N. lepida feces Metagenome

| PRJNA194130 | ENA

gut metagenome

Project description:Study of microbial community in the feces of white rhinoceroses

| PRJNA197230 | ENA

Impact of the gut microbiota on enhancer accessibility in gut intraepithelial lymphocytes

Project description:The gut microbiota impacts many aspects of host biology including immune function. One hypothesis is that microbial communities induce epigenetic changes with accompanying alterations in chromatin accessibility, providing a mechanism that allows a community to have sustained host effects even in the face of its structural or functional variation. We used ATAC-seq to define chromatin accessibility in predicted enhancer regions of intestinal αβ+ and γδ+ intraepithelial lymphocytes (IELs) purified from germ-free mice, their conventionally-raised (CONV-R) counterparts, and mice reared GF and then colonized with a CONV-R gut microbiota at the end of the suckling-weaning transition. Characterizing genes adjacent to traditional enhancers and super-enhancers revealed signaling networks, metabolic pathways, and enhancer-associated transcription factors affected by the microbiota. Our results support the notion that epigenetic modifications help define microbial community-affiliated functional features of host immune cell lineages.

2016-11-28 | GSE89646 | GEO

A Single Human-Relevant Fast Food Meal Produces Rapid Reorganization of the Gut Microbiome Revealing Unique Gut Microbe-Dependent Metabolomic Signatures

Project description:Background: More than 100 million Americans are living with metabolic syndrome, increasing their propensity to develop heart disease– the leading cause of death worldwide. A major contributing factor to this epidemic is caloric excess, often a result of consuming low cost, high calorie fast food. Several recent seminal studies have demonstrated the pivotal role of gut microbes contributing to cardiovascular disease in a diet-dependent manner. Given the central contributions of diet and gut microbiota to cardiometabolic disease, we hypothesized that novel microbial metabolites originating postprandially after fast food consumption may contribute to cardiometabolic disease progression. Methods: To test this hypothesis, we gave conventionally raised or antibiotic-treated mice a single oral gavage of a fast food slurry or a control rodent chow diet slurry and sacrificed the mice four hours later. Here, we coupled untargeted metabolomics in portal and peripheral blood, 16S rRNA gene sequencing, targeted liver metabolomics, and host liver RNA sequencing to identify novel fast food-derived microbial metabolites. Results: We successfully identified several metabolites that were enriched in portal blood, increased by fast food feeding, and essentially absent in antibiotic-treated mice. Strikingly, just four hours post-gavage, we found that fast food consumption resulted in rapid reorganization of the gut microbial community structure and drastically altered hepatic gene expression. Importantly, diet-driven reshaping of the microbiome and liver transcriptome was dependent on a non-antibiotic ablated gut microbial community. Conclusions: Collectively, these data suggest that single fast food meal is sufficient to reshape the gut microbial community yielding a unique signature of food-derived microbial metabolites. Future studies are warranted to determine if these metabolites are causally linked to cardiometabolic disease.

2021-11-14 | GSE165756 | GEO

Longitudinal analysis reveals that probiotics are a significant driver of gut microbiome development in very preterm infants

Project description:Impact of small molecules from different microbial gut community types on gene expression from preterm intestinal derived organoids

2022-07-18 | GSE208315 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data