Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mycobacterium tuberculosis

ABSTRACT: Whole-genome sequencing analysis of Mycobacterium tuberculosis in Hanoi, Vietnam

PROVIDER: PRJDB8544 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	DRR184603_1.fastq.gz	Fastqsanger.gz
	DRR184603_2.fastq.gz	Fastqsanger.gz
	DRR184604_1.fastq.gz	Fastqsanger.gz
	DRR184604_2.fastq.gz	Fastqsanger.gz
	DRR184605_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 160

Similar Datasets

Mycobacterium tuberculosis

Project description:Whole-genome sequencing analysis of Mycobacterium tuberculosis in Hanoi, Vietnam (248 strains)

| PRJDB8553 | ENA

Mycobacterium tuberculosis

Project description:Whole-genome sequencing analysis of Mycobacterium tuberculosis in Hanoi, Vietnam (Four representative strains)

| PRJDB8543 | ENA

Mycobacterium tuberculosis

Project description:Complete genome sequences of Mycobacterium tuberculosis clinical strains evoking outstanding genotype clusters in Hanoi, Vietnam

| PRJDB5607 | ENA

Mycobacterium tuberculosis

Project description:Whole-genome sequencing analysis of lineage 1 strains of Mycobacterium tuberculosis in Da Nang, Vietnam

| PRJDB6149 | ENA

Mycobacterium tuberculosis

Project description:Whole-genome sequencing analysis of Mycobacterium tuberculosis in Da Nang, Vietnam, using long-read technology

| PRJDB10954 | ENA

Mycobacterium tuberculosis

Project description:Whole-genome sequencing analysis of Mycobacterium tuberculosis in Da Nang, Vietnam, using short-read technology

| PRJDB10923 | ENA

Expression Analysis of WR99210-treated Mycobacterium tuberculosis H37Rv

Project description:Investigation of whole genome gene expression level changes in Mycobacterium tuberculosis treated with the DHFR inhibitor WR99210, compared to untreated cells. The antimycobacterial properties of WR99210 are further described in Gerum, A., Ulmer, J., Jacobus, D., Jensen, N., Sherman, D., and C. Sibley. 2002. Novel Saccharomyces cerevisiae screen identifies WR99210 analogues that inhibit Mycobacterium tuberculosis dihydrofolate reductase. Antimicrob Agents Chemother 46(11):3362-3369 [PMID:12384337]

2012-09-18 | GSE40917 | GEO

Mycobacterium tuberculosis

Project description:Mycobacterium tuberculosis whole genome sequencing

| PRJNA283583 | ENA

Gene expression analysis of Mycobacterium tuberculosis under arginine conditions

Project description:In other bacteria, arginine induces the expression of genes involved in arginine catabolism. This study obtained the identification of genes involved in the arginine metabolism of Mycobacterium tuberculosis. Mycobacterium tuberculosis was cultured with arginine or ammonium chloride as sole nitrogen source. In the log phase of growth, RNA was isolated and whole genome expression was determined. The study contains three biological replicates.

2015-04-01 | E-GEOD-67445 | biostudies-arrayexpress

Identification of gene fusion events in Mycobacterium tuberculosis that encode novel chimeric proteins

Project description:Mycobacterium tuberculosis is a facultative intracellular pathogen, responsible for causing tuberculosis. The harsh environment in which M. tuberculosis survives requires this pathogen to maintain an evolutionary advantage. However, the apparent absence of horizontal gene transfer in M. tuberculosis imposes restrictions in the ways by which evolution can occur. Large scale changes in the genome can be introduced through genome reduction, recombination events and structural variation. Here, we identify a functional chimeric protein in the ppe38-71 locus, the absence of which is known to have an impact on protein secretion and virulence. To examine whether this approach was used more often by this pathogen we further develop software that detects potential gene fusion events from multigene deletions using whole-genome sequencing data. With this software we could identify a number of other putative gene-fusion events within the genomes of M. tuberculosis isolates. We were able to demonstrate the expression of one of these gene fusions at the protein level using mass spectrometry. Therefore, gene fusions may provide an additional means of evolution for M. tuberculosis in its natural environment whereby novel proteins and functions can arise.

2020-05-12 | PXD017298 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data