Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

2009-2011 cholera outbreak in Papua New Guinea caused by atypical Vibrio cholerae El Tor

ABSTRACT: Two Vibrio cholerae isolates from the 2009-2011 cholera outbreak in Papua New Guinea have been sequenced. These two isolates are representative of near clonal set of isolates obtained during the outbreak. The genomes were sequenced using the WGS strategy. Read sets were produced on the Illumina sequencing platform (100b, PE). Genome read coverage is ~100x.

PROVIDER: PRJEB11637 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Spatio-temporal epidemiology of the cholera outbreak in Papua New Guinea, 2009-2011.

Project description:Cholera continues to be a devastating disease in many developing countries where inadequate safe water supply and poor sanitation facilitate spread. From July 2009 until late 2011 Papua New Guinea experienced the first outbreak of cholera recorded in the country, resulting in >15,500 cases and >500 deaths.Using the national cholera database, we analysed the spatio-temporal distribution and clustering of the Papua New Guinea cholera outbreak. The Kulldorff space-time permutation scan statistic, contained in the software package SatScan v9.2 was used to describe the first 8 weeks of the outbreak in Morobe Province before cholera cases spread throughout other regions of the country. Data were aggregated at the provincial level to describe the spread of the disease to other affected provinces.Spatio-temporal and cluster analyses revealed that the outbreak was characterized by three distinct phases punctuated by explosive propagation of cases when the outbreak spread to a new region. The lack of road networks across most of Papua New Guinea is likely to have had a major influence on the slow spread of the disease during this outbreak.Identification of high risk areas and the likely mode of spread can guide government health authorities to formulate public health strategies to mitigate the spread of the disease through education campaigns, vaccination, increased surveillance in targeted areas and interventions to improve water, sanitation and hygiene.

| S-EPMC4158135 | biostudies-literature

Papua New Guinea birds

Project description:Papua New Guinea birds Genome sequencing and assembly

| PRJNA637995 | ENA

Leaf samples pilot study Papua New Guinea

Project description:Pilot study on leaves from Papua New Guinea showing soil toxicity, extracted in RNAlater in one case and MQ water in another, also MQ blanks

2023-05-25 | MSV000092034 | MassIVE

Small Sample-Big Data: Integrative Indexed Systems Biology Reveals Dramatic Molecular Ontogeny over the First Week of Human Life in Papua New Guinea

Project description:This study examines the global transcriptomic profiles in peripheral blood of Papua New Guinea newborns at birth (D0) comparing with follow up at day 1 (D1), day 3 (D3), or day 7 (D7) post birth.

2019-03-20 | GSE123070 | GEO

Wave 2 strains of atypical Vibrio cholerae El Tor caused the 2009-2011 cholera outbreak in Papua New Guinea.

Project description:Vibrio cholerae is the causative agent of cholera, a globally important human disease for at least 200 years. In 2009-2011, the first recorded cholera outbreak in Papua New Guinea (PNG) occurred. We conducted genetic and phenotypic characterization of 21 isolates of V. cholerae, with whole-genome sequencing conducted on 2 representative isolates. The PNG outbreak was caused by an atypical El Tor strain harbouring a tandem repeat of the CTX prophage on chromosome II. Whole-genome sequence data, prophage structural analysis and the absence of the SXT integrative conjugative element was indicative that the PNG isolates were most closely related to strains previously isolated in South-East and East Asia with affiliations to global wave 2 strains. This finding suggests that the cholera outbreak in PNG was caused by an exotic (non-endemic) strain of V. cholerae that originated in South-East Asia.

| S-EPMC6487313 | biostudies-literature

Sediment Metagenomes Papua New Guinea

Project description:Marine metagenomes and metatranscriptomes from 3 sediment samples along a pH gradient in Papua New Guinea

| PRJEB9383 | ENA

Pygoscelis papua

Project description:Pygoscelis papua overview

| PRJNA491768 | ENA

Mastigias papua

Project description:Mastigias papua overview

| PRJNA992609 | ENA