Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

JIA-ERA

ABSTRACT: Gut microbiota of Juvenile Idiopathic arthritis

PROVIDER: PRJEB11846 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR1143910.fastq.gz	Fastqsanger.gz
	ERR1143920.fastq.gz	Fastqsanger.gz
	ERR1143930.fastq.gz	Fastqsanger.gz
	ERR1143940.fastq.gz	Fastqsanger.gz
	ERR1143950.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 75

Similar Datasets

Expression data from SPARKS CHARMS JIA cohort

Project description:Gene expression on peripheral blood mononuclear cells (PBMC) from SPARKS CHARMS juvenile idiopathic arthritis (JIA) cohort pre and post methotrexate therapy. This is the first study to our knowledge, to evaluate gene expression profiles in children with JIA before and after MTX, and to analyze genetic variation in differentially expressed genes. We have identified a gene, which may contribute to genetic variability in MTX response in JIA.

2010-09-27 | GSE23687 | GEO

Transcription profiling of peripheral blood samples from juvenile idiopathic arthritis (JIA) patients pre and post methotrexate therapy. Expression data from SPARKS CHARMS JIA cohort

2010-09-27 | E-GEOD-23687 | biostudies-arrayexpress

Gene Expression Profiles Distinguish Children with Inactive Polyarticular Juvenile Idiopathic Arthritis (JIA) with a Predilection to Flare

Project description:Gene expression profiles were obtained from 17 children with rheumatoid factor negative (RF-) polyarticular juvenile idiopathic arthritis (JIA). The disease was inactive in all patients at visit 1. Thee disease remained inactive at visit 2 for 9 patients, while the other 8 patients were experiencing a disease flare at visit 2. The goal of the study was to better understand the underlying molecular biology of flares in JIA Total RNA was obtained from PBMC at two different times in the course of disease

2013-12-14 | GSE26112 | GEO

Gene Expression Profiles Distinguish Children with Inactive Polyarticular Juvenile Idiopathic Arthritis (JIA) with a Predilection to Flare

2013-12-14 | E-GEOD-26112 | biostudies-arrayexpress

sJIA serum proteome profiling with DIA-MS

Project description:We performed a DIA-MS proteomic analysis of sera from systemic juvenile idiopathic arthritis with different activity phases using a high protein depletion process. We profiled the proteins in the sera that differed significantly in their activity phase.

2022-04-26 | PXD030413 | JPOST Repository

Transcription profiling of peripheral blood monocytes from patients with systemic juvenile idiopathic arthritis during active and inactive disease

Project description:Comaprison of PBMCs from patients with systemic juvenile idiopathic arthritis during active and inactive disease

2007-03-31 | E-MEXP-987 | biostudies-arrayexpress

human gut metagenome

Project description:The gut microbiota of children with juvenile idiopathic arthritis (Raw sequence reads)

| PRJNA562061 | ENA

Remission in Polyarticular Juvenile Idiopathic Arthritis

Project description:Identify biomarkers to predict response to therapy in polyarticular juvenile idiopathic arthritis (JIA) using gene expression microarrays.

2009-04-13 | GSE15645 | GEO

Molecular profiles of Systemic Juvenile Idiopathic Arthritis patients

Project description:Biomarker identification for diagnosis of systemic juvenile idiopathic arthritis (SJIA), an auto-inflammatory disease that presents with prolonged fevers.

2015-09-03 | GSE57183 | GEO

Transcriptomic Analysis of Isolated Monocytes from heathy donors and JIA patinets using Nanostring Technology

Project description:Among immune cells, activated monocytes play a detrimental role in chronic and viral-induced inflammatory pathologies. The uncontrolled activation of monocytes and the subsequent excessive production of inflammatory factors damage bone-cartilage joints in Juvenile Idiopathic Arthritis (JIA), a childhood rheumatoid arthritis (RA) disease. The moderate beneficial effect of current therapies and clinical trials highlights the need of alternative strategies targeting monocytes to treat RA disease. Here, we show that targeting CXCR4 with small amino compound such as the histamine analog clobenpropit (CB) inhibits spontaneous and induced-production of a set of key inflammatory cytokines by monocytes isolated from blood and synovial fluids of JIA patients. Moreover, daily intraperitoneal CB treatment of arthritic mice results in significant decrease in circulating inflammatory cytokine levels, immune cell infiltrates, joints erosion, and bone resorption leading to reduction of disease progression. These overall data show that targeting CXCR4 with CB-like molecules may represent a promising therapeutic option for chronic and viral-induced inflammatory diseases.

2023-09-21 | GSE243512 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data