Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Phillipines oral microbiome

ABSTRACT: Oral microbiome samples from the Philippines

PROVIDER: PRJEB14383 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	ERR1474570_1.fastq.gz	Fastqsanger.gz
	ERR1474570_2.fastq.gz	Fastqsanger.gz
	ERR1474580_1.fastq.gz	Fastqsanger.gz
	ERR1474580_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 63

Similar Datasets

Oral microbiome composition of Agta hunter-gatherers (16S)

Project description:To investigate the factors affecting the composition of the oral microbiome of Agta hunter-gatherers from the Philippines, we sequenced the 16S rRNA region from saliva samples from the Agta population (hunter-gatherers from Philippines) together with BaYaka (hunter-gatherers from Congo) and Palanan farmers (neighboring population of the Agta).

| EGAS00001005317 | EGA

Exploring the microbiome of oral epithelial dysplasia as a predictor of malignant progression

Project description:The objectives of this study were to establish a microbiome profile for oral epithelial dysplasia using archival lesion swab samples to characterize the community variations and the functional potential of the microbiome using 16S rRNA gene sequencing

2022-09-30 | GSE198811 | GEO

oral microbiome

Project description:oral cancer microbiome

| PRJEB51102 | ENA

Oral microbiome

Project description:Oral microbiome Targeted loci

| PRJNA690163 | ENA

Oral microbiome - Saliva samples

Project description:Oral microbiome

| PRJEB60183 | ENA

The mediating roles of the oral microbiome in saliva and subgingival sites between e-cigarette smoking and gingival inflammation

Project description:In this paper, we first report that EC smoking significantly increases the odds of gingival inflammation. Then, we seek to identify and explain the mechanism that underlies the relationship between EC smoking and gingival inflammation via the oral microbiome. We performed mediation analyses to assess if EC smoking affects the oral microbiome, which in turn affects gingival inflammation. For this, we collected saliva and subgingival samples from EC users and non-users and profiled their microbial compositions via 16S rRNA amplicon sequencing. We then performed α-diversity, β-diversity, and taxonomic differential analyses to survey the disparity in microbial composition between EC users and non-users. We found significant increases in α-diversity in EC users and disparities in β-diversity between EC users and non-users.

2022-12-09 | GSE201949 | GEO

RELMβ Sets the Threshold for Microbiome-Dependent Oral Tolerance

Project description:Tolerance to dietary antigens is critical to avoid deleterious type 2 immune responses resulting in food allergy (FA) and anaphylaxis. However, the mechanisms resulting in both the maintenance and failure of tolerance to food antigens is poorly understood. Here we demonstrate that the goblet cell-derived resistin-like molecule beta (RELMb) is a critical regulator of oral tolerance. We find that RELMb is abundant in serum in both food allergic patients and mouse models of FA. Deletion of RELMβ protects mice from FA, development of food antigen specific IgE and anaphylaxis. RELMb disrupts food tolerance through modulation of the gut microbiome by suppressing gut Lactobacilli. Tolerance is maintained via local production of indole derivatives driving FA protective RORgt+ regulatory T (Treg) cells via activation of the aryl hydrocarbon receptor (AhR). RELMb antagonism in the peri-weaning period restored oral tolerance and protected genetically prone offspring from developing FA later in life. Together, our data identify RELMb as mediating both a novel gut immune-epithelial circuit regulating tolerance to food antigens, a new mode of innate control of antigen specific adaptive immunity via microbiome editing and targetable candidates in this circuit for prevention and treatment of FA.

2022-12-27 | GSE221462 | GEO

Oral bacterial microbiome

Project description:Oral bacterial microbiome Targeted loci

| PRJNA690810 | ENA

HIV Oral Bacterial Microbiome

Project description:HIV Oral Bacterial Microbiome

| PRJEB93489 | ENA

Human oral microbiome

Project description:Human oral microbiome Raw sequence reads

| PRJNA616210 | ENA