Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Oral Microbiome

ABSTRACT: Effects of toothpaste containing enzymes and proteins on the ecology of the plaque oral microbiome

PROVIDER: PRJEB14665 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	ERR1513010_1.fastq.gz	Fastqsanger.gz
	ERR1513010_2.fastq.gz	Fastqsanger.gz
	ERR1513020_1.fastq.gz	Fastqsanger.gz
	ERR1513020_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 429

Similar Datasets

oral microbiome

Project description:oral cancer microbiome

| PRJEB51102 | ENA

Exploring the microbiome of oral epithelial dysplasia as a predictor of malignant progression

Project description:The objectives of this study were to establish a microbiome profile for oral epithelial dysplasia using archival lesion swab samples to characterize the community variations and the functional potential of the microbiome using 16S rRNA gene sequencing

2022-09-30 | GSE198811 | GEO

human oral metagenome

Project description:Human Oral Subgingival Plaque Microbiome

| PRJNA78025 | ENA

Oral microbiome

Project description:Oral microbiome Targeted loci

| PRJNA690163 | ENA

Oral microbiome - Saliva samples

Project description:Oral microbiome

| PRJEB60183 | ENA

Impact of different oral treatments on the composition of the supragingival plaque microbiome

Project description:Using a metaproteome approach in addition to a standard plaque-regrowth study, this study examined the impact of different concentrations of lactoperoxidase (LPO) in two lozenge formulations on early plaque formation, microbiome composition, and active biological processes in young orally healthy volunteers.

2022-06-29 | MSV000089755 | MassIVE

RELMβ Sets the Threshold for Microbiome-Dependent Oral Tolerance

Project description:Tolerance to dietary antigens is critical to avoid deleterious type 2 immune responses resulting in food allergy (FA) and anaphylaxis. However, the mechanisms resulting in both the maintenance and failure of tolerance to food antigens is poorly understood. Here we demonstrate that the goblet cell-derived resistin-like molecule beta (RELMb) is a critical regulator of oral tolerance. We find that RELMb is abundant in serum in both food allergic patients and mouse models of FA. Deletion of RELMβ protects mice from FA, development of food antigen specific IgE and anaphylaxis. RELMb disrupts food tolerance through modulation of the gut microbiome by suppressing gut Lactobacilli. Tolerance is maintained via local production of indole derivatives driving FA protective RORgt+ regulatory T (Treg) cells via activation of the aryl hydrocarbon receptor (AhR). RELMb antagonism in the peri-weaning period restored oral tolerance and protected genetically prone offspring from developing FA later in life. Together, our data identify RELMb as mediating both a novel gut immune-epithelial circuit regulating tolerance to food antigens, a new mode of innate control of antigen specific adaptive immunity via microbiome editing and targetable candidates in this circuit for prevention and treatment of FA.

2022-12-27 | GSE221462 | GEO

The Effects of Benoxacor on the Liver and Gut Microbiome of C57BL/6 Mice

Project description:We report the hepatotoxicity and effects of benoxacor on the gut microbiome following an acute oral exposure.

2021-10-01 | GSE172173 | GEO

Oral bacterial microbiome

Project description:Oral bacterial microbiome Targeted loci

| PRJNA690810 | ENA

HIV Oral Bacterial Microbiome

Project description:HIV Oral Bacterial Microbiome

| PRJEB93489 | ENA