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ABSTRACT: Streptococcus salivarius ATCC 7073

PROVIDER: PRJEB18413 | ENA |

REPOSITORIES: ENA

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Dataset's files

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			Action	DRS
	FRCU01.dat.gz	Other
	FRCU01.fasta.gz	Fasta.gz
	FRCU01.master.dat	Other
	FRCU01.dat.gz	Other

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Streptococcus salivarius strain:ATCC 7073 | isolate:ATCC 7073

Project description:Streptococcus salivarius ATCC 7073 genome sequencing

| PRJNA329892 | ENA

RNA sequencing of Streptococcus salivarius strains from oral cavities of Korean subjects

Project description:To investigate the subspecies level differences in the expression profiles of Streptococcus salivarius strains, we conducted the RNA sequencing analysis of Streptococcus salivarius strains.

2024-11-10 | GSE278791 | GEO

A study on the impact of the absence of the NIP or NrpR gene on gene expression of Streptococcus salivarius K12 (SAL)

Project description:NIP and NrpR forms a pair for the transcriptional regulator in Streptococcus salivarius K12 (SAL). To explore the target genes regulated by the NIP-NrpR pair in Streptococcus salivarius K12 (SAL), we generated mutants in which the NIP or NrpR gene has been knocked down through complement recombination. Comparative transcriptome profiling of WT, ▲nrpR, and nip* mutant strains revealed that the sar BGC is the major regulatory target controlled by the NIP signaling pathway in SAL.

2023-11-18 | GSE247581 | GEO

Circuitry rewiring directly couples competence to predation in the gut-dweller Streptococcus salivarius

Project description:Small distortions in transcriptional networks might lead to drastic phenotypical changes, especially in cellular developmental programs such as competence for natural transformation. Here, we report a pervasive circuitry rewiring for competence and predation interplay in commensal streptococci. Canonically, in model species of streptococci such as Streptococcus pneumoniae and Streptococcus mutans, the pheromone-based two-component system BlpRH is a central node that orchestrates the production of antimicrobial compounds (bacteriocins) and incorporates signal from the competence activation cascade. However, the human commensal Streptococcus salivarius does not contain a functional BlpRH pair and in this species, the competence signaling system ComRS directly couples bacteriocin production and competence commitment. This network shortcut might account for an optimal reaction against microbial competitors and could explain the high prevalence of S. salivarius in the human digestive tract. Moreover, the broad spectrum of bacteriocin activity against pathogenic bacteria showcases the commensal and genetically tractable S. salivarius species as a user-friendly model for natural transformation and bacterial predation.

2018-01-10 | GSE100416 | GEO

Streptococcus salivarius strain:ATCC 25975

Project description:Streptococcus salivarius strain:ATCC 25975 Genome sequencing

| PRJNA227252 | ENA

Streptococcus salivarius strain:ATCC 27945

Project description:Streptococcus salivarius strain:ATCC 27945 Genome sequencing

| PRJNA264747 | ENA

Extracellular vesicles of probiotic microorganism Streptococcus salivarius

Project description:Identification of proteins from extracellular vesicles isolated from Streptococcus salivarius. This work was financially supported by the National Science Centre, Poland (grant number 2021/43/D/NZ6/01464).

2023-05-24 | PXD039138 | Pride

GNPS_ref_Bacteria_Firmicutes_Bacilli_Lactobacillales_Streptococcaceae_Streptococcus_salivarius_RAQ001

Project description:A reference bacterial dataset of Streptococcus salivarius grown on Todd Hewitt Agar. Agar blank included

2016-10-24 | MSV000080287 | GNPS

Koduru2022 - Lactobacillus salivarius ATCC 11741

Project description:GEM reconstruction for Lactobacillus salivarius ATCC 11741

2023-11-27 | MODEL2210190008 | BioModels

Alterations of oral microbiota and impact on the gut microbiome in type 1 diabetes mellitus revealed by multi-omic analysis

Project description:Background Alterations of the gut microbiome have been linked to multiple chronic diseases. However, the drivers of such changes remain largely unknown. The oral cavity acts as a major route of exposure to exogenous factors including pathogens, and processes therein may affect the communities in the subsequent compartments of the gastrointestinal tract. Here, we perform strain-resolved, integrated multi-omic analyses of saliva and stool samples collected from eight families with multiple cases of type 1 diabetes mellitus (T1DM). Results We identified distinct oral microbiota mostly reflecting competition between streptococcal species. More specifically, we found a decreased abundance of the commensal Streptococcus salivarius in the oral cavity of T1DM individuals, which is linked to its apparent competition with the pathobiont Streptococcus mutans. The decrease in S. salivarius in the oral cavity was also associated with its decrease in the gut as well as higher abundances in facultative anaerobes including Enterobacteria. In addition, we found evidence of gut inflammation in T1DM as reflected in the expression profiles of the Enterobacteria as well as in the human gut proteome. Finally, we were able to follow transmitted strain-variants from the oral cavity to the gut at the metagenomic, metatranscriptomic and metaproteomic levels, highlighting not only the transfer, but also the activity of the transmitted taxa along the gastrointestinal tract. Conclusions Alterations of the oral microbiome in the context of T1DM impact the microbial communities in the lower gut, in particular through the reduction of “oral-to-gut” transfer of Streptococcus salivarius. Our results indicate that the observed oral-cavity-driven gut microbiome changes may contribute towards the inflammatory processes involved in T1DM. Through the integration of multi-omic analyses, we resolve strain-variant “mouth-to-gut” transfer in a disease context.

2022-10-05 | PXD031579 | Pride

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