Project description:Hundreds of DNA replication forks functioning simultaneously are essential for timely DNA duplication, but the organization of replication forks are poorly understood in mammalian cells. Here, we developed a replication-enriched in situ HiC (Repli-HiC) method to capture chromatin contacts located adjacent to replication forks and found two types of fountain-like chromatin contacts at thousands of loci. Interactions within fountain-spanning regions are confirmed by q3C-seq analysis of different stages of S phase cells.
2024-03-04 | GSE230613 | GEO
Project description:Fountain structure after DNA replication
| PRJNA1034253 | ENA
Project description:Photon-directed Multiplexed Enzymatic DNA Synthesis for Molecular Digital Data Storage
| PRJNA633646 | ENA
Project description:Terminator-free, template-independent enzymatic DNA synthesis for digital information storage