Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: WGS-based surveillance of third-generation cephalosporin-resistant Escherichia coli from bloodstream infections in Denmark

PROVIDER: PRJEB20792 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR1971300_1.fastq.gz	Fastqsanger.gz
	ERR1971300_2.fastq.gz	Fastqsanger.gz
	ERR1971310_1.fastq.gz	Fastqsanger.gz
	ERR1971310_2.fastq.gz	Fastqsanger.gz
	ERR1971320_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 1104

Similar Datasets

Project description:WGS analysis of third-generation cephalosporin resistant Escherichia coli

| PRJNA844174 | ENA

Klebsiella pneumoniae

Project description:Third generation cephalosporin-resistant Klebsiella pneumoniae isolates

| PRJNA721894 | ENA

Escherichia coli strain:field strain

Project description:CMY-2 producing third generation cephalosporin resistant E. coli

| PRJDB8169 | ENA

Escherichia coli

Project description:Third generation cephalosporin resistant Escherichia coli (CREC) genome sequencing

| PRJNA862705 | ENA

Project description:3rd generation cephalosporin resistant, uropathogenic E. coli WGS

| PRJNA891712 | ENA

Project description:third-generation cephalosporin-resistant Enterobacteriaceae in a neonatal intensive care unit

| PRJNA954276 | ENA

Project description:Population-based surveillance of Pseudomonas aeruginosa causing bloodstream infections

| PRJNA988909 | ENA

Project description:Genomic analysis of third-generation cephalosporin-resistant Escherichia coli from captive wild mammals in Tunisia

| PRJNA1367915 | ENA

An Outer Membrane Protein-Targeting Antibiotic Against Resistant Gram-Negative Bacterial Pathogens

Project description:There is an urgent need for novel antibiotics against carbapenem and 3rd generation cephalosporin-resistant Gram-negative pathogens, for which the last-resort antibiotics have lost most of their efficacy. We describe here a novel class of synthetic antibiotics that was inspired from natural product-derived scaffolds. The antibiotics have an unprecedented mechanism of action, which targets the main component (BamA) of the Bam folding machinery required for folding and insertion of ß-barrel proteins into the outer membrane of Gram-negative bacteria. This OMPTA (outer membrane protein-targeting antibiotic) class shows potent activity against multidrug-resistant Gram-negative ESKAPE pathogens and overcomes colistin-resistance both in vitro and in vivo. A clinical candidate has the potential to address life threatening Gram-negative infections with high unmet medical need.

2019-10-22 | PXD010174 | Pride

CC398 bloodstream infections in DK

Project description:Origin of LA-MRSA CC398 bloodstream infections and skin and soft tissue infections, Denmark

| PRJEB19505 | ENA