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Germline DNMT3A mutation in a mother-child pair with AML

ABSTRACT: This data relates to a mother-son pair with acute myeloid leukemia, both having a germline mutation P709S in the methyltransferase DNMT3A. Using functional assays in vitro, we demonstrate that the variant P709S has greatly reduced ability to transfer methyl groups to DNA

PROVIDER: PRJEB23099 | ENA |

REPOSITORIES: ENA

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