Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Bacteroidetes MST

ABSTRACT: Bacteroidetes pyrosequencing for microbial source tracking (MST)

PROVIDER: PRJEB2468 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR032056.fastq.gz	Fastqsanger.gz
	ERR032057.fastq.gz	Fastqsanger.gz
	ERR032058.fastq.gz	Fastqsanger.gz
	ERR032059.fastq.gz	Fastqsanger.gz
	ERR032060.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 10

Similar Datasets

MST-312: a telomerase inhibitor effectively blocking MYC oncogenic functions [ChIP-Seq]

Project description:Reactivation of the telomerase reverse transcriptase subunit, TERT, is linked to tumourigenesis due to well-documented telomere-dependent and independent functions. The aim of this study was to investigate the effect of the telomerase inhibitor, MST-312, on TERT functions, focusing in particular, on its effects on MYC stabilty and MYC-regulated pathways, in order to assess its potential as a therapeutic agent. We demonstrate that MST-312 reduces MYC levels in cancer cells, leading to reduced MYC levels on chromatin, and subsequently affecting the MYC-regulated transcriptional program. As a result, MST-312 treatment increases the survival of lymphoma-bearing mice. Mechanistically, MST-312 affects the conformation of TERT, leading to TERT/Terc dissociation, and the subsequent loss of both its telomere-dependent and independent functions. Based on the presented data, we conclude that MST-312 treatment is a promising therapeutic strategy, in particular, in MYC-driven tumorus.

2020-01-01 | GSE77061 | GEO

Bacteria from avian fecal samples

Project description:16S sequences from avian fecal samples for MST (Microbial Source Tracking)

| PRJNA300726 | ENA

Methanosarcina thermophila MST-A1

Project description:Methanosarcina thermophila MST-A1

| PRJDB14919 | ENA

MST-312: a telomerase inhibitor effectively blocking MYC oncogenic functions [array]

2020-01-01 | GSE77014 | GEO

A conserved Bacteroidetes antigen induces anti-inflammatory intestinal T lymphocytes

Project description:The microbiome contributes to the development and maturation of the immune system. In response to commensal bacteria, intestinal CD4+ T lymphocytes differentiate into functional subtypes with regulatory or effector functions. Whereas the development of small intestine intraepithelial lymphocytes that express CD4 and CD8aa homodimers (CD4IELs) depends on the microbiota, the identity of the microbial antigens recognized by CD4+ T cells that can differentiate into CD4IELs remains unknown. We identified B-hexosaminidase, a conserved enzyme across commensals of the Bacteroidetes phylum, as a driver of CD4IEL differentiation. In a mouse model of colitis, B-hexosaminidase-specific lymphocytes protected against intestinal inflammation. Thus, T cells of a single specificity can recognize a variety of abundant commensals and elicit a regulatory immune response at the intestinal mucosa.

2022-11-16 | GSE198037 | GEO

Streptomyces sp. MST-110588

Project description:Streptomyces sp. MST-110588 Genome sequencing

| PRJNA727408 | ENA

Chromatin binding of ER/TEAD/YAP in MCF-7 Cells after MST inhibitor treatment

Project description:We report YAP could repress ER positive breat cancer progression and MST inhibitor treat MCF-7 cells were used as the model.

2022-02-25 | GSE197239 | GEO

fecal

Project description:Exploring Fecal Bacterial Diversity for Microbial Source Tracking by Barcoded Pyrosequencing

| PRJEB2135 | ENA

Aspergillus nanangensis strain:MST-FP2251

Project description:Aspergillus nanangensis strain:MST-FP2251 Genome sequencing and assembly