Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptome analysis of MCF-7 breast cancer cell population to reveal the transcriptional diversity at the single cell level

ABSTRACT: Transcriptome analysis of MCF-7 breast cancer cell population to reveal the transcriptional diversity at the single cell level

PROVIDER: PRJEB2484 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR032978.fastq.gz	Fastqsanger.gz
	ERR032979.fastq.gz	Fastqsanger.gz
	ERR032980.fastq.gz	Fastqsanger.gz
	ERR032981.fastq.gz	Fastqsanger.gz

Items per page:

1 - 4 of 4

Similar Datasets

Transcriptome analysis of MCF-7 breast cancer cell population to reveal the transcriptional diversity at the single cell level

Project description:We constructed four single cell transcriptome (SCT) libraries from MCF-7 breast cancer cells and characterized their transcriptome profiles using the expression of 143 housekeeping genes as a control.

2012-03-14 | E-MTAB-609 | biostudies-arrayexpress

Transcriptome analysis of MCF-7 breast cancer cell population to reveal the transcriptional diversity at the single cell level

| S-ECPF-MTAB-609 | biostudies-other

One-pot comparative analysis and characterization of MCF-7 and MCF-10A cell lines

Project description:A comparison of different energetics based techniques for the characterization of two mammalian breast cell lines, MCF-7 a luminal A breast cancer cell line and MCF-10A a normal human breast cell line. The techniques of stability of proteins from rates of oxidation (SPROX), thermal proteome profiling (TPP), and conventional expression level analyses were compared and the relative advantages and disadvantages are discussed.

2023-02-22 | PXD036268 | Pride

INPP4B over-expressed INPP4B MCF-7 luminal breast cancer cell line

Project description:INPP4B over-expressed INPP4B MCF-7 luminal breast cancer cell line

2020-06-01 | MSV000085526 | MassIVE

E.Coli spike in to human cell line MCF-7

Project description:Spike in of 3 different amounts of E.Coli to human cell line MCF-7 with TMT10plex quantification.

2020-03-28 | PXD013277 | JPOST Repository

Expression profiling of breast cancer cell lines MCF-7 and MCF-7R4

Project description:Human breast cancer cell line MCF-7 is usually sensitive to chemotherapy drug BMS-554417, an insulin receptor (IR) and insulin-like growth factor receptor (IGFR) inhibitor. However, through step-wise increase in BMS-554417 doses in culture media, we were able able to screen and select a single MCF-7 clone that is BMS-554417 resistant. It is cross resistant to BMS-536924. This new line of MCF-7 cells was named as MCF-7R4. The transcriptome profiling of both MCF-7 and MCF-7R4 was performed using Affymetrix HG-U133 plus2.0 GeneChip arrays.

2009-11-06 | GSE18912 | GEO

Expression profiling of breast cancer cell lines MCF-7 and MCF-7R4

2009-11-05 | E-GEOD-18912 | biostudies-arrayexpress

The expression level of microRNA after knockdown of GATA3 in MCF-7 cells

Project description:The expression level of microRNA after knockdown of GATA3 in MCF-7 cells

| PRJNA529897 | ENA

HuPSA and MoPSA Atlases Reveal Novel Cell Populations and Lineage Plasticity in Prostate Cancer at Single-Cell Level

Project description:HuPSA and MoPSA Atlases Reveal Novel Cell Populations and Lineage Plasticity in Prostate Cancer at Single-Cell Level

| PRJNA1031681 | ENA

Phenotypic and microRNA characterisation of the hidden CD24+ cell population in MCF-7 breast cancer 3D spheroid culture

Project description:Introduction: In vitro 3-dimension spheroid culture has been widely used as model to enrich CD44+CD24dim/- cancer stem cells with high ALDH1 activity. However, present of the CD24+ population in the 3D spheroid also requests further attention as this side-population of cells may response differently to drug treatment comparing to the cancer stem cells. Methods: In this study, CD24+ population from the MCF-7 spheroid was sorted and subjected to spheroid formation test, stem cell markers immunofluorescence, invasion/migration test, and microRNA expression profiling. MCF-7 CD24+ cells sorted from primary spheroid reform 3D spheroid after longer period of time associated with dim expression of surface SOX-2, CD44, CD49f and Nanog comparing to the primary spheroid. Results: Remarkably, the MCF-7 CD24+ cells was found with high expression of ALDH1 protein, which subsequently contributed to higher resistant against doxorubicin and cisplatin. MicroRNA profiling has shown that absent of cancer stem cell phenotypes were contributed by the downregulation of major cancer stem cells related pathways including Hedgehog, Wnt and MAPK signalling pathways. Besides, resistance of CD24+ cells was correlated to dyregulation of cell death pathway.

2018-03-12 | GSE95598 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data