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RNA-Seq of human aortic endothelial cells with lysophosphatidylinositol against untreated controls

ABSTRACT: RNA-Seq of human aortic endothelial cells with lysophosphatidylinositol against untreated controls

PROVIDER: PRJEB25610 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	ERR2403200_1.fastq.gz	Fastqsanger.gz
	ERR2403200_2.fastq.gz	Fastqsanger.gz
	ERR2403201_1.fastq.gz	Fastqsanger.gz
	ERR2403201_2.fastq.gz	Fastqsanger.gz
	ERR2403202_1.fastq.gz	Fastqsanger.gz

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RNA-Seq of human aortic endothelial cells with lysophosphatidylcholine against untreated controls

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RNA-Seq of human aortic endothelial cells with lysophosphatidylinositol against untreated controls

Project description:Vascular Innate immune cells, such as macrophages, elicit long-term T cell-, and B cell- immune responses, by expressing danger-associated molecular pattern (DAMP) receptors, T cell co-stimulation receptors and presenting antigens to the adaptive system through major histocompatibility complex (MHC)-II. Here, we investigated whether human aortic endothelial cells (HAECs) could also be “transdifferentiated” into innate immune cells after treatment of hyperlipidemia-upregulated DAMP molecules, lysophosphatidylinositol (LPI). HAECs were treated with vehicle control or lysophosphatidylinositol (16:0) (10µM) for 18 hours.

2018-05-16 | E-MTAB-6605 | biostudies-arrayexpress

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