Project description:Investigation of gene expression profile changes upon down regulation of p63 in L3.6pl and BxPC-3 cell lines which are representative of the squamous molecular subtype in pancreatic cancer

2018-12-18 | E-MTAB-7033 | biostudies-arrayexpress

Expression profile of MCF7 and T47D human breast cancer cell lines upon treatment with the BET bromodomian inhibitor JQ1

Project description:Expression profile of MCF7 and T47D human breast cancer cell lines upon treatment with the BET bromodomian inhibitor JQ1

2017-05-08 | GSE95287 | GEO

RNA seq in PacR L3.6pl cells

Project description:Identification of regulated genes in PacR L3.6pl

2023-03-21 | E-MTAB-11737 | biostudies-arrayexpress

RNA-seq analysis of HNSCC cells after JQ1 treatment

Project description:We performed RNA sequencing (RNA-seq) of HNSCC cells to examine genome-wide gene expression pattern following JQ1 treatment. BET inhibition by JQ1 significantly inhibits a cohort of key oncogenes associate with tumorigenesis and metastasis. Suggesting BET inhibition is effective strategy to suppress the tumorigenesis and metastasis of head and neck squamous cell carcinoma.

2021-05-05 | GSE131967 | GEO

RNA-seq in HSJD-DIPG-007 cells treated with JQ1, ICG-001, JQ1 and ICG-001 and DMSO as control.

Project description:This study aims to characterize gene expression changes upon treatment with JQ1, ICG-001, and combined treatment. The general goal is to identify the mechanism for high efficacy of combinatorial treatment of BET and CBP inhibition in DIPG cells.

2020-08-01 | E-MTAB-8243 | biostudies-arrayexpress

RNA-seq analysis of HNSCC cells after JQ1 treatment

Project description:RNA-seq analysis of HNSCC cells after JQ1 treatment

| PRJNA545475 | ENA