Project description:Global warming has become a critical challenge to food safety, causing severe yield losses of major crops worldwide. Here, we report that the endophytic bacterium Enterobacter sp. SA187 induces thermotolerance of crops in a sustainable manner. Microbiome diversity of wheat plants is positively influenced by SA187 in open field agriculture, indicating that beneficial microbes can be a powerful tool to enhance agriculture in open field agriculture.

2021-02-28 | GSE147553 | GEO

Paenibacillus chitinolyticus NBRC 15660

Project description:Paenibacillus chitinolyticus NBRC 15660 genome sequencing project

| PRJDB376 | ENA

Paenibacillus chitinolyticus strain:KCCM 41400

Project description:Paenibacillus chitinolyticus strain:KCCM 41400 Genome sequencing and assembly

| PRJNA427089 | ENA

description of a novel Bradyrhizobium sp RP6T

Project description:description of a novel Bradyrhizobium sp RP6T

| PRJEB29857 | ENA

Micromonospora species WMMB482

Project description:Crude extract of marine Micromonospora sp. WMMB482

2022-08-23 | MSV000090193 | MassIVE

PARVB overexpression increases migration capability and defines high risks for endophytic growth and metastasis in tongue squamous cell carcinoma.

Project description:Tongue squamous cell carcinoma (TSCC) varies in characteristics even in early stages and is mainly classified into three subtypes, which are superficial, exophytic and endophytic types, based on a macroscopic appearance of tumor growth.Of these subtypes, endophytic tumor has a poorer prognosis because of its invasive feature and higher frequency to have metastasis. To understand a molecular mechanism of endophytic subtype and identify biomarkers, we performed comprehensive microarray analysis for mRNAs from clinical biopsy sampleswhich were classified into subtypes and found overexpression of parvin-beta (PARVB) gene significantly related to endophytic type. PARVB is known to play a critical role in actin reorganization and focal adhesions. Knocking down PARVB expression in vitrocaused apparent decreases in cell migration and wound healing, implying that PARVB has a crucial role in cellular motility. Moreover, metastasis-free survival was significantly lowered in patients with higher PARVB expression. Therefore overexpression of PARVB is a candidate biomarker for endophytic tumor and metastasis and may be clinically applicable for decision making of an adjuvant therapy in TSCC. Twenty seven OCT embedded tissues were used to extract total RNA. Then RNAs were amplified, biotinylated, fragmented and hybridized on GeneChip Human Genome U133 plus 2.0 arrays.

2015-12-31 | E-GEOD-52915 | biostudies-arrayexpress

PARVB overexpression increases migration capability and defines high risks for endophytic growth and metastasis in tongue squamous cell carcinoma.

2015-12-31 | GSE52915 | GEO