Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Secrets of the hospital underbelly: abundance of antimicrobial resistance genes in hospital wastewater reflects hospital antimicrobial use and inpatient length of stay

ABSTRACT: Secrets of the hospital underbelly: abundance of antimicrobial resistance genes in hospital wastewater reflects hospital antimicrobial use and inpatient length of stay

PROVIDER: PRJEB34410 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR3519521_1.fastq.gz	Fastqsanger.gz
	ERR3519521_2.fastq.gz	Fastqsanger.gz
	ERR3519522_1.fastq.gz	Fastqsanger.gz
	ERR3519522_2.fastq.gz	Fastqsanger.gz
	ERR3519523_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 16

Similar Datasets

Project description:EMG produced TPA metagenomics assembly of PRJEB34410 data set (Secrets of the hospital underbelly: abundance of antimicrobial resistance genes in hospital wastewater reflects hospital antimicrobial use and inpatient length of stay).

| PRJEB39978 | ENA

Cerebrospinal fluid proteomic profiling reflects biological heterogeneity of early-onset Alzheimer's disease dementia

Project description:Cerebrospinal fluid proteomic profiling reflects biological heterogeneity of early-onset Alzheimer's disease dementia from The First Affiliated Hospital of USTC

2023-02-16 | PXD040216 |

Exploring the diversity and antibiogram of the soil around a tertiary care hospital and a university precinct in southern In-dia: A pilot study

Project description:This study identified and compared the bacterial diversity and the antimicrobial resistance profile of clinically relevant isolates around a newly developed hospital and university precinct

2024-02-27 | GSE225419 | GEO

Influence of perioperative step volume on complication rate and length of hospital stay after colorectal cancer surgery

Project description:Interventions: Group 1: Patients assigned to the intervention group will receive a pedometer preoperatively with a defined step goal of 7500 steps daily. Postoperatively, the patients receive a predefined target of daily steps to be achieved in the first days after surgery. On the first postoperative day these are at least 500 steps, on the 2nd postoperative day 1000 steps, on the 3rd postoperative day 2000 steps, on the 4th postoperative day 3000 steps and on the 5th postoperative day and 4000 steps. The actual steps taken are documented regardless of whether the goal is reached. Group 2: The control group receives a pedometer preoperatively with the request to document the daily steps taken without a defined step target. The pedometer continues to be used postoperatively and the number of steps is documented during the inpatient stay. Primary outcome(s): Length of hospital stay Study Design: Allocation: Randomized controlled study; Masking: Blinded (masking used); Control: active; Assignment: parallel; Study design purpose: treatment

| 72433 | ecrin-mdr-crc

Influence of the severity of postoperative complications after major visceral surgery on the length of hospital stay

Project description:Interventions: Group 1: For patients with elective interventions, which fall under the interventions defined by us, the length of stay in hospital and the degree of complication are recorded on the basis of their patient files. Primary outcome(s): length of stay in hospital Study Design: Allocation: ; Masking: ; Control: ; Assignment: ; Study design purpose: other

| 72218 | ecrin-mdr-crc

The antimicrobial peptide-sensing system aps of Staphylococcus aureus

Project description:Staphylococcus aureus is a leading cause of hospital-associated infections. In addition, highly virulent strains of methicillin-resistant S. aureus (MRSA) are currently spreading outside health care settings. Survival in the human host is largely defined by the ability of S. aureus to resist mechanisms of innate host defense, of which antimicrobial peptides form a key part especially on epithelia and in neutrophil phagosomes. Here we demonstrate that the antimicrobial-peptide sensing system aps of the standard community-associated MRSA strain MW2 controls resistance to cationic antimicrobial peptides. The core of aps-controlled resistance mechanisms comprised the D-alanylation of teichoic acids (dlt operon), the incorporation of cationic lysyl-phosphatidylglycerol (L-PG) in the bacterial membrane (mprF), and the vraF/vraG putative antimicrobial peptide transporter. Further, the observed increased production of L-PG under the influence of cationic antimicrobial peptides was accompanied by the up-regulation of lysine biosynthesis. In noticeable difference to the aps system of S. epidermidis, only selected antimicrobial peptides strongly induced the aps response. Heterologous complementation with the S. epidermidis apsS gene indicated that this is likely caused by differences in the short extracellular loop of ApsS that interacts with the inducing antimicrobial peptide. Our study shows that the antimicrobial peptide sensor system aps is functional in the important human pathogen S. aureus, significant interspecies differences exist in the induction of the aps gene regulatory response, and aps inducibility is clearly distinguishable from effectiveness towards a given antimicrobial peptide. Keywords: Wild type control vs treated vs mutant Wild type untreated in triplicate is compared to wild type treated in triplicate along with three mutants in triplicate with and without treatment of indolicidin, totalling 30 samples

2008-04-06 | E-GEOD-8400 | biostudies-arrayexpress

The antimicrobial peptide-sensing system aps of Staphylococcus aureus

2008-04-07 | GSE8400 | GEO

Diploptera punctata isolate:Stay&Tobe

Project description:Diploptera punctata isolate:Stay&Tobe Genome sequencing and assembly

| PRJNA803029 | ENA

Transcriptomic analysis of the rpn12a-236 stay-green mutant

Project description:The 19S proteasome mutant rpn12a-236 exhibits a stay-green phenotype upon individually darkened leaf treatment (IDL). To gain insight into the molecular mechanisms conferring this extended longevity to rpn12a-236 in response to darkness, we performed RNA-seq analysis on WT and mutant leaves sampled after 0 hour (light control), 6 hours, 1 day, 3 days and 6 days of IDL treatment.

2022-09-02 | GSE212121 | GEO

Hospital Microbiome

Project description:Hospital Microbiome

| PRJEB31632 | ENA