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Metabolic alterations of liver Connexin-43 knockout in mice

ABSTRACT: Metabolic alterations of liver Connexin-43 knockout in mice

PROVIDER: PRJEB40894 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	ERR4695876_1.fastq.gz	Fastqsanger.gz
	ERR4695876_2.fastq.gz	Fastqsanger.gz
	ERR4695877_1.fastq.gz	Fastqsanger.gz
	ERR4695877_2.fastq.gz	Fastqsanger.gz
	ERR4695878_1.fastq.gz	Fastqsanger.gz

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Project description:The atypical chemokine receptor 3 (ACKR3) plays a pivotal role in directing the migration of various cellular populations and its over-expression in various tumors promotes cell proliferation and invasiveness. The intracellular cellular pathways transducing ACKR3-dependent effects remain poorly characterized, an issue we addressed by characterizing the the interactome of recombinant ACKR3 expressed in HEK293T cells. Among the ACKR3-interacting proteins identified, we focused on the gap junction protein Connexin 43 (Cx43).

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