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Single Cell RNA Sequencing of human bone marrow LT-HSCs.

ABSTRACT: Single Cell RNA Sequencing of human bone marrow LT-HSCs.

PROVIDER: PRJEB42050 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	ERR5000344_1.fastq.gz	Fastqsanger.gz
	ERR5000344_2.fastq.gz	Fastqsanger.gz
	ERR5000345_1.fastq.gz	Fastqsanger.gz
	ERR5000345_2.fastq.gz	Fastqsanger.gz
	ERR5000346_1.fastq.gz	Fastqsanger.gz

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Expression data from LT-HSCs from bone marrow non-irradiated, 8Gy CDR and 8Gy FLASH total body irradiated mice

Project description:Total body irradiation (TBI) of mice using two dose rates, conventional dose rate (CDR) versus flash dose rate (FLASH), induced transient decrease of number of LT-HScs in bone marrow and a total recovery of these cells 15 days after TBI We used microarrays to detail the global programme of gene expression underlying the recovery of LT-HSCs and identified distinct classes of up or down- regulated genes according the modality of irradiation

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