Project description:Rats vary in their susceptibilities to Toxoplasma gondii infection depending on the rat strain. Compared to the T. gondii-susceptible Brown Norway (BN) rat, the Lewis (LEW) rat is extremely resistant to T. gondii. Thus, these two rat strains are ideal models for elucidating host mechanisms that are important for host resistance to T. gondii infection. Therefore, in an attempt to unravel molecular factors directing the protective early innate immune responses in the LEW rat, we performed RNA sequencing analysis of the LEW versus BN rat, with or without T. gondii infection.
Project description:Examination of gene expression associated with hypoxia treatment of rat strains FHH ( Fawn Hooded Hypertensive) and BN(Brown Norway).
Project description:Examination of gene expression associated with hypoxia treatment of rat strains FHH (Fawn Hooded Hypertensive) and BN (Brown Norway).
Project description:Examination of gene expression changes during hypoxia of the Dahl salt sensitive (SS) rat and SS13BN consomic rat. SS13BN rats are derived from introgression of chromosome 13 from Brown Norway (BN) rat into the SS genetic background.
Project description:Examination of gene expression changes during hypoxia of the Dahl salt sensative (SS) rat and SS13BN cosomic rat. SS13BN rats are derived from introgression of chromosome 13 from the Brown Norway (BN) rat into the SS genetic background.
Project description:Examination of gene expression changes during hypoxia of the Dahl salt sensitive (SS) rat and SS7BN consomic rat. SS7BN rats are derived from introgression of chromosome 7 from the Brown Norway (BN) rat into the SS genetic background.
