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RNA-Seq of Acute Myeloid Leukemia Cell lines with a 3q-aberration and Acute Myeloid Leukemia cell line controls

ABSTRACT: RNA-Seq of Acute Myeloid Leukemia Cell lines with a 3q-aberration and Acute Myeloid Leukemia cell line controls

PROVIDER: PRJEB5234 | ENA |

REPOSITORIES: ENA

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Dataset's files

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			Action	DRS
	ERR412874_1.fastq.gz	Fastqsanger.gz
	ERR412874_2.fastq.gz	Fastqsanger.gz
	ERR412875_1.fastq.gz	Fastqsanger.gz
	ERR412875_2.fastq.gz	Fastqsanger.gz
	ERR412876_1.fastq.gz	Fastqsanger.gz

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RNA-Seq of Acute Myeloid Leukemia Cell lines with a 3q-aberration and Acute Myeloid Leukemia cell line controls

Project description:Using RNA deep sequencing we determined gene expression patterns and expression genotypes in Acute Myeloid Leukemia (AML) cell lines harboring a 3q-aberration. These cell lines specifically overexpress the gene EVI1 which plays a significant part in leukomogenesis. Additionally we RNA sequenced AML cell lines that overexpress EVI1 resulting from different genetic causes or do not express EVI1 at all.

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