Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptome effects of persistent organic pollutants in the liver of Atlantic cod (Gadus morhua)

ABSTRACT: Transcriptome effects of persistent organic pollutants in the liver of Atlantic cod (Gadus morhua)

PROVIDER: PRJEB57091 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR10431400_1.fastq.gz	Fastqsanger.gz
	ERR10431400_2.fastq.gz	Fastqsanger.gz
	ERR10431401_1.fastq.gz	Fastqsanger.gz
	ERR10431401_2.fastq.gz	Fastqsanger.gz
	ERR10431402_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 94

Similar Datasets

Transcriptome effects of persistent organic pollutants in the liver of Atlantic cod (Gadus morhua)

Project description:In the North Sea and adjacent North Atlantic coastal areas fish experience relatively high levels of persistent organic pollutants. The aim of this study is to compare the mode of actions of environmentally relevant concentrations of halogenated compounds and their mixtures in Atlantic cod. Juvenile male cod were fed mixtures of chlorinated (PCBs, DDT analogs, chlordane, lindane and toxaphene), brominated (PBDEs) and fluorinated (Perfluorooctanesulfonate/PFOS) compounds for one month. One group received a mixture of all three compounds. Transcriptome analysis of liver samples was performed to identify the main affected pathways. Accumulated levels of chemicals in cod liver reflected concentrations found in wild fish. Pathway analysis revealed that the treatment effects by each of the three groups of chemicals (chlorinated, brominated and fluorinated) converged on activation of the unfolded protein response (UPR). The results of our transcriptomics analysis suggest that the UPR pathway is a sensitive common target of halogenated organic environmental pollutants

2023-01-04 | E-MTAB-12338 | biostudies-arrayexpress

Long-term exposure of Atlantic Cod (Gadus morhua) to components of produced water

Project description:Male and female Atlantic cod (Gadus morhua) liver transcriptome analysis following in vivo waterborne PAH, AP and phenol exposure

2011-03-24 | E-MTAB-121 | biostudies-arrayexpress

Effects of pollution on liver of Atlantic cod

Project description:Effects of oil pollution and persistent organic pollutants (POPs) on the glycerophospholipids in the liver of male Atlantic cod (Gadus morhua)

2012-11-01 | E-MTAB-1209 | biostudies-arrayexpress

Effects on the lipid metabolism of Atlantic cod (Gadus morhua) after in vivo exposure with Ppar agonists

Project description:Lipid metabolism is essential in maintaining energy homeostasis in multicellular organisms. In vertebrates, the peroxisome proliferator-activated receptors (PPARs, NR1C) regulate the expression of many genes involved in these processes. Four Ppar subtypes from Atlantic cod (Gadus morhua) were recently cloned and characterized. However, the downstream regulatory role of Ppars in cod lipid metabolism is presently not well understood or described. Here we study the involvement of Atlantic cod Ppar subtypes in systemic regulation of lipid metabolism using the model agonists WY14,643, GW501516, and tetradecylthioacetic acid, employing a multiple omics approach after an in vivo exposure situation.

2022-09-20 | PXD031739 | Pride

Gadus morhua

Project description:Gadus morhua (Atlantic cod), fGadMor2

| PRJNA1084037 | ENA

The study of Atlantic cod (Gadus morhua) spleen global gene expression response to intraperitoneal injection with formalin-killed atypical Aeromonas salmonicida.

Project description:This study was performed to validate the newly developed CGP Atlantic cod 20K oligonucleotide microarray. Atlantic cod (Gadus morhua) received an intraperitoneal injection of either formalin-killed, atypical Aeromonas salmonicida (Asal) or PBS and transcriptional profiles of spleen tissues from Asal-injected fish were compared to those from pre-injection control fish and PBS-injected control fish. Gene expression profiles resulting from this study were compared to those from suppression subtractive hybridization library studies, that were previously performed on the same samples, and to literature. Gene expression patterns of single genes were confirmed by QPCR analysis. This study has shown that the newly developed CGP Atlantic cod 20K oligo microarray platform is a valuable tool for cod genomic research.

2010-11-05 | GSE22312 | GEO

Gadus morhua

Project description:The Atlantic cod, Gadus morhua, overview

| PRJNA43385 | ENA

Gadus morhua

Project description:Population genomics in Atlantic cod, Gadus morhua

| PRJNA78311 | ENA

Gadus morhua

Project description:Gadus morhua (Atlantic cod) genomic and transcriptomic data

| PRJNA1084038 | ENA

Gadus morhua

Project description:Gadus morhua (Atlantic cod) genome assembly, fGadMor2, principal haplotype