Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Carbapenemase-Producing gram-negative bacteria in Djibouti city, Djibouti

ABSTRACT: Carbapenemase-Producing gram-negative bacteria in Djibouti city, Djibouti

PROVIDER: PRJEB58617 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
		Other
	ERR10710700_1.fastq.gz	Fastqsanger.gz
	ERR10710700_2.fastq.gz	Fastqsanger.gz
	ERR10710701_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 64

Similar Datasets

Non-carbapenemase-producing Gram negative bacteria

Project description:Non-carbapenemase-producing Gram negative bacteria, including ESBLs, AmpCs and non-beta-lactamase beta-lactams resistance mechanisms in clinical isolates from MDU Public Health Lab, Victoria, Australia Genome sequencing and assembly

| PRJNA842191 | ENA

Gram negative Bacilli

Project description:Characterization of carbapenemase-producing Gram negative Bacilli Assembly

| PRJNA391501 | ENA

Clinical Evaluation of Advanced MALDI-TOF MS for Carbapenemase Subtyping in Gram-negative Isolates

Project description:The spread of carbapenemase-producing Enterobacterales (CPE) is emerging as a significant clinical concern in tertiary hospitals and in particular, long-term care facilities with deficiencies in infection control. This study aims to evaluate an advanced matrix-assisted laser desorption/ionization mass spectrometry (A-MALDI) method for the identification of carbapenemases and further discrimination of their subtypes in clinical isolates. The A-MALDI method was employed to detect CPE target proteins. Enhancements were made to improve detectability and mass accuracy through the optimization of MALDI-TOF settings and internal mass calibration. A total of 581 clinical isolates were analyzed, including 469 CPE isolates (388 KPC, 51 NDM, 40 OXA, and 2 GES) and 112 carbapenemase-negative isolates. Clinical evaluation of the A-MALDI demonstrated 100% accuracy and precision in identifying all the collected CPE isolates. Additionally, A-MALDI successfully discriminated individual carbapenemase subtypes (KPC-2 or KPC-3/4; OXA-48 or OXA-181 or OXA-232; GES-5 or GES-24) and also differentiated co-producing carbapenemase strains (KPC & NDM; KPC & OXA; KPC & GES; NDM & OXA), attributed to its high mass accuracy and simultaneous detection capability. A-MALDI is considered a valuable diagnostic tool for accurately identifying CPE and carbapenemase’s subtypes in clinical isolates. It may also aid in selecting appropriate antibiotics for each carbapenemase subtype. Ultimately, we expect that the A-MALDI method will contribute to preventing the spread of antibiotic resistance and improving human public health.

2024-11-26 | PXD058284 | Pride

Clinical Evaluation of Advanced MALDI-TOF MS for Carbapenemase Subtyping in Gram-negative Isolates

2024-11-25 | PXD046179 | Pride

Gram Negative Carbapenemase Detection Genome sequencing and assembly

Project description:Gram Negative Carbapenemase Detection Genome sequencing and assembly

| PRJNA292904 | ENA

Environmental Surveillance of ESBL and Carbapenemase-Producing Gram-Negative Bacteria from a Ghanaian Tertiary Hospital

Project description:Environmental Surveillance of ESBL and Carbapenemase-Producing Gram-Negative Bacteria in a hospital in Ghana

| PRJEB46496 | ENA

Carbapenemase Producing E.coli Ireland

Project description:Carbapenemase Producing E.coli Ireland

| PRJEB19435 | ENA

Carbapenemase Producing Organisms

Project description:Clinical Carbapenemase Producing Organism Genomic Surveillance

| PRJNA1030769 | ENA

Whole transcriptomic analysis of mechanisms of tolerance and resistance to chlorhexidine in carbapenemase-producing Klebsiella pneumoniae clinical strains

Project description:The increasing resistence and/or bacterial tolerance to bactericides, such as chlorhexidine, causes worrisome public health problems. Using transcriptomical and microbiological studies, we analysed the molecular mechanisms associated with the adaptation to chlorhexidine in two carbapenemase-producing strains of Klebsiella pneumoniae belonging ST258-KPC3 and ST846-OXA48.

2020-03-21 | GSE147316 | GEO

Carbapenemase-producing Enterobacteriaceae

Project description:Carbapenemase-producing Enterobacteriaceae isolated from Hong Kong, China

| PRJNA595034 | ENA