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RNA-seq of adrenal cortical cells of Cacna1h-deficient mice against wild-type controls

ABSTRACT: RNA-seq of adrenal cortical cells of Cacna1h-deficient mice against wild-type controls

PROVIDER: PRJEB62546 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	ERR11474847_1.fastq.gz	Fastqsanger.gz
	ERR11474847_2.fastq.gz	Fastqsanger.gz
	ERR11474848_1.fastq.gz	Fastqsanger.gz
	ERR11474848_2.fastq.gz	Fastqsanger.gz
	ERR11474849_1.fastq.gz	Fastqsanger.gz

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Mass spectrometry-based proteomics discovery of prognostic biomarkers in adrenal cortical carcinoma

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Adrenal stress response is an essential host response against lethal T cell activation

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RNA-seq of adrenal cortical cells of Cacna1h-deficient mice against wild-type controls

Project description:CaV3.2 (encoded by Cacna1h gene) is necessary for the generation of calcium oscillations by maintaining voltage oscillations in zona glomerulosa cells of mice. However, Cacna1h knockout mice have normal plasma aldosterone levels, suggesting additional calcium entry pathways. We used RNA-seq to investigate such pathways in the murine zona glomerulosa. We want to investigate whether other calcium channels or transporters were upregulated to compensate for the loss of CaV3.2.

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