Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Anopheles insecticide resistance genes on the Bijagos Archipelago

ABSTRACT: Genomic screening of Anopheles insecticide resistance genes on the Bijagos Archipelago

PROVIDER: PRJEB62886 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR12217000_1.fastq.gz	Fastqsanger.gz
	ERR12217000_2.fastq.gz	Fastqsanger.gz
	ERR12217100_1.fastq.gz	Fastqsanger.gz
	ERR12217100_2.fastq.gz	Fastqsanger.gz
	ERR12217001_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 478

Similar Datasets

Investigation of cis-regulation of metabolic insecticide resistance related gene expression in Anopheles gambiae using allelic imbalance

Project description:Malaria control relies on insecticides targeting the mosquito vector, but is being increasingly compromised by insecticide resistance. Elevated expression of metabolic enzymes frequently drives resistance. In diploids, gene expression is regulated both in cis, by regulatory sequences on the same chromosome, and by trans acting factors, affecting both alleles equally. Differing levels of transcription can be caused by mutations in cis-regulatory modules, but few cis-regulatory modules controlling the expression of genes that determine insecticide resistance have been identified. Genes potentially under differential cis-regulation between bendiocarb resistant and susceptible Anopheles gambiae strains were identified by counting transcripts produced from maternal and paternal alleles in F1 hybrids of these strains (allelic specific expression). Cis regulatory module sequences controlling gene expression in insecticide resistance relevant tissues such as midgut, Malpighian tubules and legs were predicted using a previously established machine learning method. These predictions included CRM proximal to both genes under differential cis regulation and genes that show consistent differential expression patterns in multiple resistant Anopheles strains.

2023-11-22 | GSE241768 | GEO

Nkya et al 2014 - Insecticide resistance mechanisms associated with different environments in the malaria vector Anopheles gambiae. A case study in Tanzania

Project description:Nine Anopheles gambiae populations were sampled in three areas of Tanzania showing contrasting agriculture activity, urbanization and usage of insecticides for vector control. Insecticide resistance levels were measured in larvae and adults through bioassays with deltamethrin, DDT and bendiocarb. A microarray approach was used for identifying transcription level variations associated to different environments and insecticide resistance. the Ifakara strain originating from central Tanzania and susceptible to all insecticides was used as a reference strain.

2013-10-31 | E-MEXP-3987 | biostudies-arrayexpress

Transcription profiling by array of insecticide resistance in field populations of Anopheles funestus in Benin

Project description:Transcriptome profiling of insecticide resistant field populations of Anopheles funestus from Benin compared to a susceptible lab strain FANG

2013-12-16 | E-MTAB-1578 | biostudies-arrayexpress

miRNAs and insecticide resistance

Project description:The role of miRNAs in insecticide resistance in Anopheles gambiae

| PRJEB35264 | ENA

Anopheles funestus amidst a South/North shift in the role of key resistance genes across Malawi

Project description:Resistance to pyrethroids, the only insecticide approved for bednets, threatens control of the major malaria vector, Anopheles funestus, in Malawi. To improve the management of such resistance countrywide, it is crucial to understand the dynamics and mechanisms driving resistance in the field. In this study the levels of insecticide resistance were determined across the highly endemic densely populated lake and southern agricultural area. Insecticide resistance to pyrethoids was assessed using standardized WHO bioassay methods and resistant mosquitoes were hybridized to susceptible mosquitoes. This microarray analysis revealed the key role of cytochrome P450 genes such as CYP6P9a, CYP6P9b and CYP6M7. However, a significant shift in the over-expression of these CYP450s was detected across a south/north transect, with CYP6M7 more highly over-transcribed in the two northern collection sites and the tandemly duplicated genes, CYP6P9a and CYP6P9b, more greatly over-transcribed in the south.

2016-02-12 | E-MTAB-3342 | biostudies-arrayexpress

Proteomic investigation on Anopheles gambiae in Burkina Faso related to insecticide pressures from different climatic regions

Project description:In Sub-Saharan Africa, Anopheles gambiae Giles (Diptera: Culicidae) largely contributes to malaria transmission, in direct relation to environmental conditions influencing the vector ecology. Therefore, our study aimed to compare the proteomes of An. gambiae according to varying insecticide pressures associated to cotton crops also integrating different population origins from two climatic regions of Burkina Faso.

2020-03-09 | PXD016300 | Pride

Transcriptomic profiling of insecticide resistant field Anopheles gambiae from Tanzania compared to fully susceptible laboratory strains

Project description:Comparative gene expression profiling of Anopheles gambiae insecticide resistant field strain from an area of a major insecticide treated bednet randomised control trial

2021-06-03 | E-MTAB-10580 | biostudies-arrayexpress

Transcriptomic profiling of insecticide resistant field Anopheles funestus from Tanzania compared to a fully susceptible laboratory strain

Project description:Comparative gene expression profiling of Anopheles funestus insecticide resistant field strain from an area of a major insecticide treated bednet randomised control trial

2021-06-03 | E-MTAB-10579 | biostudies-arrayexpress

Insecticide resistance mechanisms Myzus persicae: Genotypes Insecticide vs. Genotypes Control

Project description:Transcripcional responses in three genotypes of Muzus persicae, each exhibiting different resistance mechanisms, in response to an anti.cholinesterase insecticide

2013-01-01 | GSE37310 | GEO

Transcription profiling by array of a multi insecticide resistant strain of Anopheles gambiae

Project description:Transcriptome profiling of a multi insecticide resistant strain of Anopheles gambiae from Burkina Faso compared to a susceptible strain Ngousso from Cameroon.

2013-04-12 | E-MTAB-1083 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data