Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

TRANSCRIPTOME ANALYSIS DURING THE METAMORPHOSIS OF THE ASCIDIAN CIONA INTESTINALIS

ABSTRACT: TRANSCRIPTOME ANALYSIS DURING THE METAMORPHOSIS OF THE ASCIDIAN CIONA INTESTINALIS

PROVIDER: PRJEB66283 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

TRANSCRIPTOME ANALYSIS DURING THE METAMORPHOSIS OF THE ASCIDIAN CIONA INTESTINALIS

Project description:Tunicates, including ascidians, are recognized as the true “sister group” of vertebrates and are emerging as models to study the development and degeneration of central nervous system (CNS). Ascidian larvae have the typical chordate body plan that includes a dorsal neural tube. During their metamorphosis, a deep tissue reorganization takes place, with some tissues that degenerate while others develop to become functional during the adult life. The larval CNS also degenerates and most neurons disappear, making room to the formation of adult CNS. The genome of the ascidian Ciona intestinalis has been sequenced and annotated, with several CNS specific genes that have been characterized, revealing specification mechanisms shared with humans. These features make ascidian metamorphosis a good model to study the mechanisms underlying physiological CNS degeneration and to compare them to the pathological condition typical of neurodegenerative diseases. In order to shed light on the molecular determinants of C. intestinalis metamorphosis and neurodegeneration, we analyzed its transcriptome at three stages of development: swimming larva (SwL, Hotta stage 28), settled larva (SetL, Hotta stage 32) and metamorphosing larva (MetL, Hotta stage 34). Supported by SoE-SEED-2020 Grant, University of Milan.

2024-08-31 | E-MTAB-13385 | biostudies-arrayexpress

Ciona intestinalis (ascidian): control vs. TBT exposed

Project description:Transcriptional profiling of Ciona intestinalis comparing ethanol exposed asidian (control) with TBT exposed ascidian.

2010-07-20 | GSE22995 | GEO

Ciona intestinalis (ascidian): control vs. TBT exposed

Project description:Transcriptional profiling of Ciona intestinalis comparing ethanol exposed asidian (control) with TBT exposed ascidian. Two conditions experiment comparing ethanol exposed asidian (control) with TBT exposed ascidian.

2010-07-20 | E-GEOD-22995 | biostudies-arrayexpress

Identification of differentially expressed genes in the mutant tail regression failed (trf) in Ciona intestinalis.

Project description:Tunicate ascidians exhibit metamorphosis that converts tadpole, swimming larva into immotile adult. In ascidian Ciona intestinalis, the mutant tail regression failed (trf) which shows defects in the metamorphosis was previously reported (Nakayama-Ishimura et al., 2009). In the metamorphosis process, trf larvae settle normally with their adhesive papillae, but do not start tail regression, papillae retraction and sensory vesicle retraction, while development of adult organs proceed. To understand the molecular mechanism of the metamorphosis, microarray analysis of trf mutant was performed.

2020-06-30 | GSE124672 | GEO

Ciona intestinalis

Project description:Ciona intestinalis (ascidian): control vs. TBT exposed

| PRJNA127833 | ENA

Gene expression of ovary and neural complex in adult Ciona intestinalis

Project description:To compare with new Ciona intestinalis microarray NimbleGen 135k, we peformed gene expression analysis of GPL14686. Total RNAs from common samples with a part of NimbleGen's analysis are used for this analysis. Ovary and Neural Complex from adult Ciona intestinalis, duplicate, 2 time points during spawning

2011-11-05 | E-GEOD-33498 | biostudies-arrayexpress

Life cycle of Ciona intestinalis

Project description:Recent whole-genome studies and in-depth expressed sequence tag (EST) analyses have identified most of the developmentally relevant genes in the urochordate, Ciona intestinalis. In this study, we made use of a large-scale oligo-DNA microarray to further investigate and identify genes with specific or correlated expression profiles. This large-scale oligo-DNA microarray for C. intestinalis should facilitate the understanding of global gene expression and gene networks during the development and ageing of a basal chordate. Keywords: gene expression, development, ageing, life cycle

2007-06-20 | GSE6308 | GEO

Gene expression profiles of unfertilized eggs of Ciona intestinalis

Project description:The transcriptome of unfertilized eggs of Ciona intestinalis was determined with microarrays.

2013-10-29 | GSE45500 | GEO

Ciona intestinalis

Project description:Ciona intestinalis transcriptome analysis

| PRJNA32863 | ENA

Ciona intestinalis

Project description:Ciona intestinalis transcriptome project

| PRJDA46247 | ENA