Project description:We performed RNA sequencing of primary human iNKT cell lines pulsed with Porphyromonas gingivalis (Pg) compared to basal activated iNKT cells.
Project description:Wild type Porphyromonas gingivalis strain ATCC33277 (V3176) and PG1626 - deficient mutant (V3177) were grown in iron replete conditions was used to compare to Porphyromonas gingivalis strains grown in iron chelated conditions.
Project description:We performed RNA sequencing of primary human iNKT cell lines pulsed with Fn or αGalCer, the prototype agonist of iNKT cells. Fn-primed iNKT cells showed an enriched neutrophil chemotaxis gene signature, including the chemokine C-X-C and C-C motif ligand family genes. αGalCer-primed iNKT cells presented an IFNγ/cytotoxic-related gene signature.
Project description:Porphyromonas gingivalis and Treponema denticola are periodontalpathogens that are associated with the severity and progression of periodontal diseases. This study investigates the gene expression of Porphyromonas gingivalis during co-culture with Treponema denticola
Project description:Porphyromonas gingivalis and Treponema denticola are periodontalpathogens that are associated with the severity and progression of periodontal diseases. this study investigates the gene expression of Treponema denticola during co-culture with Porphyromonas gingivalis.
Project description:The role of ECF sigma factors PG0162, PG01660 were involved in virulence regulationin Porphyromonas gingivalis was published Yuetan Dou, Devon Osbourne, Rachelle McKenzie, Hansel M Fletcher. (2010) Involvement of extracytoplasmic function sigma factors in virulence regulation in Porphyromonas gingivalis W83. FEMS Microbiology Letter, 312(1):24-32.