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LpPhlPrat

ABSTRACT: Phleum pratense (timothy grass), genomic and transcriptomic data

PROVIDER: PRJEB81088 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	ERR13800636.fastq.gz	Fastqsanger.gz
	ERR13800637.fastq.gz	Fastqsanger.gz
	ERR13800638.fastq.gz	Fastqsanger.gz
	ERR13802765_1.fastq.gz	Fastqsanger.gz
	ERR13802765_2.fastq.gz	Fastqsanger.gz

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Project description:This study investigated temporal transcriptomic changes in response to nasal allergen challenge of titrated timothy grass pollen. This is an open single-center observational study conducted outside the pollen season. Twelve participants with seasonal allergic rhinitis underwent a control (diluent) challenge followed by nasal allergen challenge after an interval of 14 days. On each challenge day, nasal challenge with control or titrated timothy grass pollen (Aquagen, phleum pratense; ALK) was administered. Peripheral blood was collected before nasal challenge (baseline) and at 3, 6 and 24 hours following challenge. RNA was extracted from whole blood and CD4 cells for microarray experiment using Affymetrix Human Gene 1.0 ST arrays.

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