FOXP4-mediated induction of PTK7 activates the Wnt/β-catenin pathway and promotes ovarian cancer development
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA1013114 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| SRR25918414_1.fastq.gz | Fastqsanger.gz | |||
| SRR25918414_2.fastq.gz | Fastqsanger.gz | |||
| SRR25918415_1.fastq.gz | Fastqsanger.gz | |||
| SRR25918415_2.fastq.gz | Fastqsanger.gz | |||
| SRR25918416_1.fastq.gz | Fastqsanger.gz |
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Project description:The canonical Wnt/β-catenin signaling pathway plays multiple roles during Xenopus gastrulation, including posteriorization of the neural plate, patterning of the mesoderm, and induction of the neural crest. Wnt signaling stabilizes β-catenin, which then activates target genes. However, few targets of this signaling pathway that mediate early developmental processes are known. Here we sought to identify transcriptional targets of the Wnt/β-catenin signaling pathway using a genome-wide approach.
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