Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Global mapping of H3K27ac and RPB1 occupancy upon WNK463 treatment

ABSTRACT: Global mapping of H3K27ac and RPB1 occupancy upon WNK463 treatment

PROVIDER: PRJNA1023927 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR26282700_1.fastq.gz	Fastqsanger.gz
	SRR26282700_2.fastq.gz	Fastqsanger.gz
	SRR26282701_1.fastq.gz	Fastqsanger.gz
	SRR26282701_2.fastq.gz	Fastqsanger.gz
	SRR26282702_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 24

Similar Datasets

Global mapping of H3K27ac and RPB1 occupancy upon WNK463 treatment

Project description:ChIP-seq for H3K27ac and RPB1 in JJN3 cells treated with DMSO or WNK463

2024-04-16 | GSE244630 | GEO

H3K27ac ChIP upon NeuroD1 overexpression

Project description:H3K27ac ChIP upon NeuroD1 overexpression

| PRJNA714252 | ENA

Modification of C-terminal Domain (CTD) of RPB1 plays a role in transcriptome change upon salt stress

Project description:Transctriptome profiling of CTD-14 repeats, 2A, 5A mutants responding to 0.7N NaCl for 30mins. The study shows that phosphorylation at Ser5 sites plays a role in normal induction and repression of genes upon NaCl stress. The CTD14 strains harbors a plasmid expressing RPB1 with 14 wild-type CTD repeats. 5A strains carries a plasmid expressing a chimeric RPB1 in which the CTD was composed of 5 repeats of CTD-serine 5 substituted with Ala followed by 7 wild-type-sequenced repeats. The 2A strains carrys 8 repeats of CTD-serine 2 substituted with alanine followed by 7 wild-type-sequenced repeats.

2014-12-03 | GSE60700 | GEO

Modification of C-terminal Domain (CTD) of RPB1 plays a role in transcriptome change upon salt stress

2014-12-03 | E-GEOD-60700 | biostudies-arrayexpress

Genome-wide maps of GATA1, TAL1, and H3K27ac occupancy in erythroid precursors

Project description:We report the occupancy of GATA1 and TAL1, two erythroid transcription factors, and H3K27ac histone modification in human erythroid precursors.

2017-01-10 | GSE93372 | GEO

Genetic and pharmacological evidence for kinetic competition between alternative poly(A) sites in yeast - 4tU cordycepin treatment with rpb1 slow mutant

Project description:mPAT approach using an anchored oligo-dT (TV12VN) primer to determine changes to 3'UTR length in yeast with a slow RNA polymerase II mutant rpb1-1, complemented with wild-type RPB1 or a slow rpb1 mutant plasmid, upon cordycepin treatment and new transcription using 4-thiouracil (4tU) labelling of RNA. This appears as a T to C conversion in sequencing reads.

2021-06-25 | GSE160994 | GEO

Expression profiling of rpb1-12XWTCTD and rpb1-12XS2ACTD fission yeast strains.

Project description:In fission yeast, the nuclear-localized Lsk1p-Lsc1p-Lsg1p cyclin dependent kinase complex is required for the reliable execution of cytokinesis and is also required for Ser-2 phosphorylation RNA pol II carboxy terminal domain. To address whether alterations in CTD phosphorylation might selectively alter expression of cytokinesis genes, expression profiling of site-directed CTD mutants was performed. Strains bearing the rpb1-12XCTD and rpb1-12XS2ACTD mutations were grown to mid-log phase in YES media and treated with 0.5uM LatA (or the solvent control, DMSO) for three hours at 30C. Three biological replicates were performed.

2011-08-31 | E-GEOD-31369 | biostudies-arrayexpress

Genome-wide maps of Spt6 occupancy in yeast strains with mutations in Spt6 and Rpb1

Project description:Genome-wide maps of Spt6 occupancy in yeast strains with mutations in Spt6 and Rpb1

| PRJNA385007 | ENA

Genome-wide maps of Spt6 occupancy in yeast strains with mutations in Spt6 and Rpb1

Project description:We determined that the tandem SH2 domain of S. cerevisae Spt6 binds the linker region of the RNA polymerase II subunit Rpb1, rather than the expected sites in its heptad repeat domain. The 4 nM binding affinity requires phosphorylation at Rpb1 S1493 and either T1471 or Y1473. Crystal structures showed that pT1471 binds the canonical SH2 pY site while pS1493 binds an unanticipated pocket 70 Å distant. Remarkably, the pT1471 phosphate occupies the phosphate-binding site of a canonical pY complex, while Y1473 occupies the position of a canonical pY side chain, with the combination of pT and Y mimicking a pY moiety. Biochemical data and modeling indicate that pY1473 can form an equivalent interaction, and we find that pT1471/pS1493 and pY1473/pS1493 combinations occur in vivo. ChIP-seq and genetic analyses demonstrate the importance of these interactions for recruitment of Spt6 to sites of transcription and for the maintenance of repressive chromatin.

2017-10-24 | GSE98405 | GEO

PGR genome occupancy and the H3K27ac histone mark profile in mouse uteri at gestation day 13

Project description:PGR genome occupancy and H3K27ac histone mark profiles in pregnant mouse uterine specimens were documented by ChIP-seq to investigate downstream targets of the progesterone receptor and candidate partner transcription regulators.

2022-09-21 | GSE199099 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data