Project description:Murine trophoblast organoids contain trophoblast cell types. We used CRISPR SCREENING to analyze the trophoblast organoids derived from TS (mTOs).
Project description:Murine trophoblast organoids contain trophoblast cell types. We used single cell RNA sequencing (scRNA-seq) to analyze the cellular composition of trophoblast organoids derived from placentae (mPOs).
Project description:To identify essential gene responding to anti-PD-1 immunotherapy, we performed in vivo Genome-scale CRISPR-Cas9 knockout screening. We found that cohesin complex invovled in regulation of anti-PD-1 immunotherapy.