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Bacillus subtilis

ABSTRACT: Subpopulation array data, Veening et al.

OTHER RELATED OMICS DATASETS IN: BIOMD0000000240

PROVIDER: PRJNA102897 | ENA |

REPOSITORIES: ENA

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M-CGH data from Bacillus subtilis strains from both subspecies and Bacillus vallismortis

Project description:This series represents the work described in the publication Bacillus subtilis Genome Diversity by Earl et al. (Journal of Bacteriology, accepted) Keywords: comparative genomic hybridization

2006-12-13 | GSE6498 | GEO

Tiling array hybridizations of genomic DNA from Bacillus subtilis 168.

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Project description:In this study two genome-reduced Bacillus subtilis strains lacking about 36% of dispensable genetic information were constructed using a markerless and scarless deletion method. In order to analyze the consequences of the deletions for the bacteria, a multi-omics characterization of the reference strain Δ6 (Westers et al., 2003; PMID 12949151) and the two deletion strains was carried out. Bacteria were cultivated in complex medium supplemented with glucose, and samples of the same cultures were subjected to metabolome, proteome, and transcriptome analyses.These revealed a massive re-organization of metabolism as well as substantial changes in the transcriptome and the proteome.

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